Cloning and analysis of reverse transcript P160 genomes of Abelson murine leukemia virus
about
Deletion of an N-terminal regulatory domain of the c-abl tyrosine kinase activates its oncogenic potentialTransformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein.Oncogenic v-Abl tyrosine kinase can inhibit or stimulate growth, depending on the cell context.Isolation of temperature-sensitive Abelson virus mutants by site-directed mutagenesisIsolation of temperature-sensitive tyrosine kinase mutants of v-abl oncogene by screening with antibodies for phosphotyrosine.The extreme carboxyl terminus of v-Abl is required for lymphoid cell transformation by Abelson virus.Gag influences transformation by Abelson murine leukemia virus and suppresses nuclear localization of the v-Abl proteinTemperature-sensitive mutants of Abelson murine leukemia virus deficient in protein tyrosine kinase activity.Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc: conditional regulation of c-myc transcription by temperature-sensitive v-ablOnly site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity.The minimum transforming region of v-abl is the segment encoding protein-tyrosine kinase.A membrane-associated, carbohydrate-modified form of the v-abl protein that cannot be phosphorylated in vivo or in vitroCellular RNA homologous to the Abelson murine leukemia virus transforming gene: expression and relationship to the viral sequence.Isolation of antibodies for phosphotyrosine by immunization with a v-abl oncogene-encoded protein
P2860
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P2860
Cloning and analysis of reverse transcript P160 genomes of Abelson murine leukemia virus
description
1983 nî lūn-bûn
@nan
1983年の論文
@ja
1983年論文
@yue
1983年論文
@zh-hant
1983年論文
@zh-hk
1983年論文
@zh-mo
1983年論文
@zh-tw
1983年论文
@wuu
1983年论文
@zh
1983年论文
@zh-cn
name
Cloning and analysis of reverse transcript P160 genomes of Abelson murine leukemia virus
@en
type
label
Cloning and analysis of reverse transcript P160 genomes of Abelson murine leukemia virus
@en
prefLabel
Cloning and analysis of reverse transcript P160 genomes of Abelson murine leukemia virus
@en
P2093
P2860
P1433
P1476
Cloning and analysis of reverse transcript P160 genomes of Abelson murine leukemia virus
@en
P2093
P2860
P304
P407
P577
1983-03-01T00:00:00Z