The low-abundance U11 and U12 small nuclear ribonucleoproteins (snRNPs) interact to form a two-snRNP complex
about
The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosomePrp5 bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNAEvolutionary conservation of minor U12-type spliceosome between plants and humansConservation of functional features of U6atac and U12 snRNAs between vertebrates and higher plantsThe Herpesvirus saimiri small nuclear RNAs recruit AU-rich element-binding proteins but do not alter host AU-rich element-containing mRNA levels in virally transformed T cellsIdentification of novel small RNAs using comparative genomics and microarraysU12DB: a database of orthologous U12-type spliceosomal intronsIdentification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in DrosophilaThe significant other: splicing by the minor spliceosomeThe minor spliceosomal protein U11/U12-31K is an RNA chaperone crucial for U12 intron splicing and the development of dicot and monocot plants.AT-AC pre-mRNA splicing mechanisms and conservation of minor introns in voltage-gated ion channel genes.The U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11-59K proteinRibonucleoprotein multimers and their functions.Small nuclear RNAs U11 and U12 modulate expression of TNR-CFTR mRNA in mammalian kidneysThe role of overlapping U1 and U11 5' splice site sequences in a negative regulator of splicingA limited number of pseudouridine residues in the human atac spliceosomal UsnRNAs as compared to human major spliceosomal UsnRNAsBranchpoint selection in the splicing of U12-dependent introns in vitroIn vitro assembly of coiled bodies in Xenopus egg extractPRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa.Mapping the small RNA content of simian immunodeficiency virions (SIV)Comprehensive splice-site analysis using comparative genomics.Initial recognition of U12-dependent introns requires both U11/5' splice-site and U12/branchpoint interactionsFunctionally important structural elements of U12 snRNAA U1-U2 snRNP interaction network during intron definitionRare scleroderma autoantibodies to the U11 small nuclear ribonucleoprotein and to the trimethylguanosine cap of U small nuclear RNAsA base-pairing interaction between U2 and U6 small nuclear RNAs occurs in > 150S complexes in HeLa cell extracts: implications for the spliceosome assembly pathway.Computational screen for spliceosomal RNA genes aids in defining the phylogenetic distribution of major and minor spliceosomal components.Mutational analysis of the U12-dependent branch site consensus sequence.The assembly of a spliceosomal small nuclear ribonucleoprotein particle.Anti-U11/U12 RNP antibodies in systemic sclerosis: a new serologic marker associated with pulmonary fibrosis.Autoantibody profiles in systemic sclerosis: predictive value for clinical evaluation and prognosis.Biomarkers in the management of scleroderma: an update.The U11-48K protein contacts the 5' splice site of U12-type introns and the U11-59K protein.RNA G-Quadruplexes in Biology: Principles and Molecular Mechanisms.Nucleoplasmic organization of small nuclear ribonucleoproteins in cultured human cells.Two regions promote U11 small nuclear ribonucleoprotein particle binding to a retroviral splicing inhibitor element (negative regulator of splicing).Proximity of the U12 snRNA with both the 5' splice site and the branch point during early stages of spliceosome assemblyU1-mediated exon definition interactions between AT-AC and GT-AG introns.The Arabidopsis U12-type spliceosomal protein U11/U12-31K is involved in U12 intron splicing via RNA chaperone activity and affects plant development.Mutations in the U11/U12-65K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U12 snRNA.
P2860
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P2860
The low-abundance U11 and U12 small nuclear ribonucleoproteins (snRNPs) interact to form a two-snRNP complex
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
The low-abundance U11 and U12 ...... ct to form a two-snRNP complex
@en
type
label
The low-abundance U11 and U12 ...... ct to form a two-snRNP complex
@en
prefLabel
The low-abundance U11 and U12 ...... ct to form a two-snRNP complex
@en
P2860
P356
P1476
The low-abundance U11 and U12 ...... ct to form a two-snRNP complex
@en
P2093
J A Steitz
K M Wassarman
P2860
P304
P356
10.1128/MCB.12.3.1276
P407
P577
1992-03-01T00:00:00Z