HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase - Wikidata - awgldk - TriplyDB

HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase

HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase

http://www.wikidata.org/entity/Q37021560

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Highlights on distinctive structural and functional properties of HTLV Tax proteins The HTLV-1 Tax protein inhibits formation of stress granules by interacting with histone deacetylase 6 HTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma-A Tale of Two Proteins: Tax and HBZ Activation of the DNA Damage Response by RNA Viruses How does HTLV-1 cause adult T-cell leukaemia/lymphoma (ATL)?Modes of Human T Cell Leukemia Virus Type 1 Transmission, Replication and Persistence The DNA damage response induced by infection with human cytomegalovirus and other viruses Modulation of DNA damage and repair pathways by human tumour viruses Purification of FANCD2 sub-complexes.Complex cell cycle abnormalities caused by human T-lymphotropic virus type 1 Tax.Differential role of PKC-induced c-Jun in HTLV-1 LTR activation by 12-O-tetradecanoylphorbol-13-acetate in different human T-cell lines.Chromatin at the intersection of viral infection and DNA damage Induction of reactive oxygen species by human T-cell leukemia virus type 1 tax correlates with DNA damage and expression of cellular senescence marker.Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.The viral oncoprotein tax sequesters DNA damage response factors by tethering MDC1 to chromatin.The DNA damage response in viral-induced cellular transformation Interaction between HIV-1 Tat and DNA-PKcs modulates HIV transcription and class switch recombination.HCMV-infected cells maintain efficient nucleotide excision repair of the viral genome while abrogating repair of the host genome.Activation of WIP1 phosphatase by HTLV-1 Tax mitigates the cellular response to DNA damage CHK2 kinase in the DNA damage response and beyond Human T-lymphotropic type 1 virus p30 inhibits homologous recombination and favors unfaithful DNA repair.The human T-cell leukemia virus type 1 oncoprotein tax controls forkhead box O4 activity through degradation by the proteasome Human T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis.Move or die: the fate of the Tax oncoprotein of HTLV-1.DNA repair mechanisms and human cytomegalovirus (HCMV) infection.The Sumo-targeted ubiquitin ligase RNF4 regulates the localization and function of the HTLV-1 oncoprotein Tax.How the DNA damage response determines the fate of HTLV-1 Tax-expressing cells.What's the damage? The impact of pathogens on pathways that maintain host genome integrity Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy.DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation HTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathways Wip1 and p53 contribute to HTLV-1 Tax-induced tumorigenesis HTLV-I Tax-Mediated Inactivation of Cell Cycle Checkpoints and DNA Repair Pathways Contribute to Cellular Transformation: "A Random Mutagenesis Model"WIP1 deficiency inhibits HTLV-1 Tax oncogenesis: novel therapeutic prospects for treatment of ATL?Potential of Radiation-Induced Cellular Stress for Reactivation of Latent HIV-1 and Killing of Infected Cells Dimerization and a novel Tax speckled structure localization signal are required for Tax nuclear localization.Viral manipulation of DNA repair and cell cycle checkpoints HSP90 protects the human T-cell leukemia virus type 1 (HTLV-1) tax oncoprotein from proteasomal degradation to support NF-κB activation and HTLV-1 replication WRN-targeted therapy using inhibitors NSC 19630 and NSC 617145 induce apoptosis in HTLV-1-transformed adult T-cell leukemia cells.

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HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase

http://www.wikidata.org/entity/Q37021560

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 27 October 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

HTLV-1 Tax oncoprotein subvert ...... o DNA-dependent protein kinase

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HTLV-1 Tax oncoprotein subvert ...... DNA-dependent protein kinase.

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type

label

HTLV-1 Tax oncoprotein subvert ...... o DNA-dependent protein kinase

@en

HTLV-1 Tax oncoprotein subvert ...... DNA-dependent protein kinase.

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prefLabel

HTLV-1 Tax oncoprotein subvert ...... o DNA-dependent protein kinase

@en

HTLV-1 Tax oncoprotein subvert ...... DNA-dependent protein kinase.

@nl

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Journal of Biological Chemistry

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HTLV-1 Tax oncoprotein subvert ...... o DNA-dependent protein kinase

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Abdelali Haoudi

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Gary M Kupfer

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Kimberly A Fryrear

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O John Semmes

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S Mehdi Belgnaoui

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Sarah S Durkin

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Saurabh K Gupta

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Valia T Mihaylova

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Xin Guo

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P2860

Discovery of adult T-cell leukemia

Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cells

Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks.

Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair.

DNA double-strand breaks: signaling, repair and the cancer connection

Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

The DNA-dependent protein kinase

ATM and related protein kinases: safeguarding genome integrity

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

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36311-36320

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scholarly article

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10.1074/JBC.M804931200

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52

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283

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2008-10-27T00:00:00Z

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18957425

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Human T-lymphotropic virus 1

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2605996

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