Ligand binding promotes prion protein aggregation--role of the octapeptide repeats
about
Loss of Octarepeats in two processed prion pseudogenes in the red squirrel, Sciurus vulgarisA 2cM genome-wide scan of European Holstein cattle affected by classical BSE.Instability of the octarepeat region of the human prion protein gene.Copper alters aggregation behavior of prion protein and induces novel interactions between its N- and C-terminal regions.A multistage pathway for human prion protein aggregation in vitro: from multimeric seeds to β-oligomers and nonfibrillar structures.Copper-induced structural conversion templates prion protein oligomerization and neurotoxicity.Pathogenic mutations within the hydrophobic domain of the prion protein lead to the formation of protease-sensitive prion species with increased lethality.Insights into the mechanisms of copper dyshomeostasis in amyotrophic lateral sclerosis.Glycosaminoglycan sulfation determines the biochemical properties of prion protein aggregates.Divergent heparin-induced fibrillation pathways of a prion amyloidogenic determinant.Zinc, copper, and carnosine attenuate neurotoxicity of prion fragment PrP106-126.Do prion protein gene polymorphisms induce apoptosis in non-mammals?Substitutions of PrP N-terminal histidine residues modulate scrapie disease pathogenesis and incubation time in transgenic mice.Recombinant PrP and Its Contribution to Research on Transmissible Spongiform Encephalopathies.Interplay between the hydrophobic effect and dipole interactions in peptide aggregation at interfaces.
P2860
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P2860
Ligand binding promotes prion protein aggregation--role of the octapeptide repeats
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
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2008年學術文章
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2008年學術文章
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name
Ligand binding promotes prion protein aggregation--role of the octapeptide repeats
@en
Ligand binding promotes prion protein aggregation--role of the octapeptide repeats.
@nl
type
label
Ligand binding promotes prion protein aggregation--role of the octapeptide repeats
@en
Ligand binding promotes prion protein aggregation--role of the octapeptide repeats.
@nl
prefLabel
Ligand binding promotes prion protein aggregation--role of the octapeptide repeats
@en
Ligand binding promotes prion protein aggregation--role of the octapeptide repeats.
@nl
P2093
P2860
P1433
P1476
Ligand binding promotes prion protein aggregation--role of the octapeptide repeats
@en
P2093
Chaoyang Li
Man-Sun Sy
Nancy Pham
Robert B Petersen
Shaoman Yin
Shin-Chung Kang
Shuiliang Yu
P2860
P304
P356
10.1111/J.1742-4658.2008.06680.X
P407
P577
2008-11-01T00:00:00Z