Essential nontranslational functions of tRNA synthetases.
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Mutations of human NARS2, encoding the mitochondrial asparaginyl-tRNA synthetase, cause nonsyndromic deafness and Leigh syndromeRecent advances in the biology and drug targeting of malaria parasite aminoacyl-tRNA synthetasesEvolutionary Limitation and Opportunities for Developing tRNA Synthetase Inhibitors with 5-Binding-Mode ClassificationUrzymology: experimental access to a key transition in the appearance of enzymesModification of the wobble uridine in bacterial and mitochondrial tRNAs reading NNA/NNG triplets of 2-codon boxesWars2 is a determinant of angiogenesis.Plasmodium falciparum mitochondria import tRNAs along with an active phenylalanyl-tRNA synthetaseUndercover: gene control by metabolites and metabolic enzymesA human tRNA synthetase is a potent PARP1-activating effector target for resveratrolEssentiality Assessment of Cysteinyl and Lysyl-tRNA Synthetases of Mycobacterium smegmatisProtein Translation Enzyme lysyl-tRNA Synthetase Presents a New Target for Drug Development against Causative Agents of Loiasis and SchistosomiasisElaborate uORF/IRES features control expression and localization of human glycyl-tRNA synthetaseWhy study moonlighting proteins?The crystal structure of human GlnRS provides basis for the development of neurological disorders.SerRS-tRNASec complex structures reveal mechanism of the first step in selenocysteine biosynthesis.tRNA synthetase counteracts c-Myc to develop functional vasculature.Competitive binding between Seryl-tRNA synthetase/YY1 complex and NFKB1 at the distal segment results in differential regulation of human vegfa promoter activity during angiogenesis.Human tRNA synthetase catalytic nulls with diverse functions.Natural aminoacyl tRNA synthetase fragment enhances cardiac function after myocardial infarction.Association of aminoacyl-tRNA synthetases gene polymorphisms with the risk of congenital heart disease in the Chinese Han populationGenome-scale identification and characterization of moonlighting proteins.The cultural divide: exponential growth in classical 2D and metabolic equilibrium in 3D environments.Aminoacyl-tRNA synthetase complexes in evolution.Evolutionary and structural annotation of disease-associated mutations in human aminoacyl-tRNA synthetases.Identification of a gamma interferon-activated inhibitor of translation-like RNA motif at the 3' end of the transmissible gastroenteritis coronavirus genome modulating innate immune responseDominant, toxic gain-of-function mutations in gars lead to non-cell autonomous neuropathology.Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase"...Rewritten in the skin": clues to skin biology and aging from inherited disease.Aminoacyl-tRNA synthetase dependent angiogenesis revealed by a bioengineered macrolide inhibitor.Organization of the multiaminoacyl-tRNA synthetase complex and the cotranslational protein folding.Calpain Cleaves Most Components in the Multiple Aminoacyl-tRNA Synthetase Complex and Affects Their FunctionsNeurodegenerative disease-associated mutants of a human mitochondrial aminoacyl-tRNA synthetase present individual molecular signatures.The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.MiSynPat: An integrated knowledge base linking clinical, genetic, and structural data for disease-causing mutations in human mitochondrial aminoacyl-tRNA synthetases.Assembly of Lipoic Acid on Its Cognate Enzymes: an Extraordinary and Essential Biosynthetic Pathway.Identification of protein interfaces within the multi-aminoacyl-tRNA synthetase complex: the case of lysyl-tRNA synthetase and the scaffold protein p38Identification and Characterization of Potential Biomarkers by Quantitative Tissue Proteomics of Primary Lung Adenocarcinoma.Regulated capture by exosomes of mRNAs for cytoplasmic tRNA synthetasesThe Aeromonas salmonicida subsp. salmonicida exoproteome: global analysis, moonlighting proteins and putative antigens for vaccination against furunculosis.The Werner syndrome RECQ helicase targets G4 DNA in human cells to modulate transcription.
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Essential nontranslational functions of tRNA synthetases.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on March 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Essential nontranslational functions of tRNA synthetases.
@en
Essential nontranslational functions of tRNA synthetases.
@nl
type
label
Essential nontranslational functions of tRNA synthetases.
@en
Essential nontranslational functions of tRNA synthetases.
@nl
prefLabel
Essential nontranslational functions of tRNA synthetases.
@en
Essential nontranslational functions of tRNA synthetases.
@nl
P2860
P356
P1476
Essential nontranslational functions of tRNA synthetases.
@en
P2093
Paul Schimmel
P2860
P2888
P304
P356
10.1038/NCHEMBIO.1158
P577
2013-03-01T00:00:00Z