The CAMKK2-AMPK kinase pathway mediates the synaptotoxic effects of Aβ oligomers through Tau phosphorylation
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Role of MicroRNA in Governing Synaptic PlasticityLinking Mitochondria to Synapses: New Insights for Stress-Related Neuropsychiatric DisordersTau: The Center of a Signaling Nexus in Alzheimer's DiseaseThe roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer diseaseMetabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress.The dendritic hypothesis for Alzheimer's disease pathophysiology.The Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's DiseasePre-symptomatic activation of antioxidant responses and alterations in glucose and pyruvate metabolism in Niemann-Pick Type C1-deficient murine brainPosttraumatic stress disorder-like induction elevates β-amyloid levels, which directly activates corticotropin-releasing factor neurons to exacerbate stress responses.Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn.Tau protein is essential for stress-induced brain pathologyFamily-based genome scan for age at onset of late-onset Alzheimer's disease in whole exome sequencing dataRoles of tau protein in health and disease.Dissecting the role of AMP-activated protein kinase in human diseases.AMPK signaling in the nucleus accumbens core mediates cue-induced reinstatement of cocaine seekingSynergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease.Acetylation: a new key to unlock tau's role in neurodegenerationInhibition of AMP-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β.Models of β-amyloid induced Tau-pathology: the long and "folded" road to understand the mechanism.Tau aggregation and its interplay with amyloid-β.The central role of AMP-kinase and energy homeostasis impairment in Alzheimer's disease: a multifactor network analysisPurinergic receptor activation facilitates astrocytic GABAB receptor calcium signallingModulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's DiseaseStabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity.Selective dendritic susceptibility to bioenergetic, excitotoxic and redox perturbations in cortical neurons.Structural insight into the mechanism of synergistic autoinhibition of SAD kinasesSynaptic Amyloid-β Oligomers Precede p-Tau and Differentiate High Pathology Control Cases.Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain.AMPK Signaling in the Dorsal Hippocampus Negatively Regulates Contextual Fear Memory Formation.Alternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots.AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo.The importance of tau phosphorylation for neurodegenerative diseases(ADP-ribose) polymerase 1 and AMP-activated protein kinase mediate progressive dopaminergic neuronal degeneration in a mouse model of Parkinson's disease.CaMKK2 Suppresses Muscle Regeneration through the Inhibition of Myoblast Proliferation and Differentiation.Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance.FcγRIIb-SHIP2 axis links Aβ to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model.Metformin plays a dual role in MIN6 pancreatic β cell function through AMPK-dependent autophagy.Regulatory B Subunits of Protein Phosphatase 2A Are Involved in Site-specific Regulation of Tau Protein Phosphorylation.Calcium regulation of neural rhythms, memory and Alzheimer's disease.Involvement of 'stress-response' kinase pathways in Alzheimer's disease progression.
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The CAMKK2-AMPK kinase pathway mediates the synaptotoxic effects of Aβ oligomers through Tau phosphorylation
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on April 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The CAMKK2-AMPK kinase pathway ...... rs through Tau phosphorylation
@en
The CAMKK2-AMPK kinase pathway ...... s through Tau phosphorylation.
@nl
type
label
The CAMKK2-AMPK kinase pathway ...... rs through Tau phosphorylation
@en
The CAMKK2-AMPK kinase pathway ...... s through Tau phosphorylation.
@nl
prefLabel
The CAMKK2-AMPK kinase pathway ...... rs through Tau phosphorylation
@en
The CAMKK2-AMPK kinase pathway ...... s through Tau phosphorylation.
@nl
P2093
P2860
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The CAMKK2-AMPK kinase pathway ...... rs through Tau phosphorylation
@en
P2093
Anton Maximov
Franck Polleux
Georges Mairet-Coello
Julien Courchet
Virginie Courchet
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P304
P356
10.1016/J.NEURON.2013.02.003
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P577
2013-04-01T00:00:00Z