Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability sporadic colorectal cancer in African Americans
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NGX6 gene mediated by promoter methylation as a potential molecular marker in colorectal cancerSLC5A8 gene, a transporter of butyrate: a gut flora metabolite, is frequently methylated in African American colon adenomasSporadic early-onset colorectal cancer is a specific sub-type of cancer: a morphological, molecular and genetics study.Excess of proximal microsatellite-stable colorectal cancer in African Americans from a multiethnic study.Different patterns of DNA methylation of the two distinct O6-methylguanine-DNA methyltransferase (O6-MGMT) promoter regions in colorectal cancer.Microsatellite instability in colorectal cancer-the stable evidence.MLH1 promoter methylation frequency in colorectal cancer patients and related clinicopathological and molecular featuresIdentification of novel mutations by exome sequencing in African American colorectal cancer patientsEffectors of epidermal growth factor receptor pathway: the genetic profiling ofKRAS, BRAF, PIK3CA, NRAS mutations in colorectal cancer characteristics and personalized medicine.Microbiome analysis of stool samples from African Americans with colon polyps.Molecular analysis of colorectal tumors within a diverse patient cohort at a single institution.Epigenetics could explain some Moroccan population colorectal cancers peculiarities: microsatellite instability pathway exploration.Promoter methylation of ITF2, but not APC, is associated with microsatellite instability in two populations of colorectal cancer patients.Somatic gene mutations in African Americans may predict worse outcomes in colorectal cancer.Development and progression of colorectal neoplasia.Prevalence of KRAS, BRAF, and PIK3CA somatic mutations in patients with colorectal carcinoma may vary in the same population: clues from Sardinia.Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion.The role of EGFR monoclonal antibodies (MoABs) cetuximab/panitumab, and BRAF inhibitors in BRAF mutated colorectal cancer.Racial disparities in advanced-stage colorectal cancer survivalPrognostic impact of mutation profiling in patients with stage II and III colon cancerReduced Representation Bisulfite Sequencing Determination of Distinctive DNA Hypermethylated Genes in the Progression to Colon Cancer in African AmericansA meta-analysis of MSI frequency and race in colorectal cancer.An integrative CGH, MSI and candidate genes methylation analysis of colorectal tumors.Patterns of Sociodemographic and Clinicopathologic Characteristics of Stages II and III Colorectal Cancer Patients by Age: Examining Potential Mechanisms of Young-Onset DiseaseTargeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer.Molecular and prognostic heterogeneity of microsatellite-unstable colorectal cancer.Emerging anticancer therapeutic targets and the cardiovascular system: is there cause for concern?Implementing prognostic and predictive biomarkers in CRC clinical trials.Hypermethylation of adenomatosis polyposis coli-2 and its tumor suppressor role in retinoblastoma.KRAS mutation detection and prognostic potential in sporadic colorectal cancer using high-resolution melting analysis.Racial Differences in BRAF/KRAS Mutation Rates and Survival in Stage III Colon Cancer Patients.Systematic immunohistochemical screening for mismatch repair and ERCC1 gene expression from colorectal cancers in China: Clinicopathological characteristics and effects on survival.Spectrum of somatic EGFR, KRAS, BRAF, PTEN mutations and TTF-1 expression in Brazilian lung cancer patients.A Microbiomic Analysis in African Americans with Colonic Lesions Reveals Streptococcus sp.VT162 as a Marker of Neoplastic Transformation.Distinct molecular features of colorectal cancer in Ghana.Exploring racial differences in outcome and treatment for metastatic colorectal cancer: results from a large prospective observational cohort study (BRiTE).The specific methylation characteristics of cancer related genes in Chinese colorectal cancer patients.Combined methylation of p16 and hMLH1 (CMETH2) discriminates a subpopulation with better prognosis in colorectal cancer patients with microsatellite instability tumors.Mutations in BRAF correlate with poor survival of colorectal cancers in Chinese population.High frequency of genes' promoter methylation, but lack of BRAF V600E mutation among Iranian colorectal cancer patients.
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Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability sporadic colorectal cancer in African Americans
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 03 February 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Distinct BRAF (V600E) and KRAS ...... al cancer in African Americans
@en
Distinct BRAF
@nl
type
label
Distinct BRAF (V600E) and KRAS ...... al cancer in African Americans
@en
Distinct BRAF
@nl
prefLabel
Distinct BRAF (V600E) and KRAS ...... al cancer in African Americans
@en
Distinct BRAF
@nl
P2093
P2860
P1476
Distinct BRAF (V600E) and KRAS ...... al cancer in African Americans
@en
P2093
Duane T Smoot
Edward L Lee
Francis Giardiello
Hassan Ashktorab
Hassan Brim
Krishan Kumar
Mehdi Nouraie
P2860
P304
P356
10.1158/1078-0432.CCR-08-1029
P407
P577
2009-02-03T00:00:00Z