Biochemical basis for the essential genetic requirements of RecA and the beta-clamp in Pol V activation.
about
A new model for SOS-induced mutagenesis: how RecA protein activates DNA polymerase VTranslesion DNA synthesis and mutagenesis in prokaryotes.Translesion DNA Synthesis.Increase in dNTP pool size during the DNA damage response plays a key role in spontaneous and induced-mutagenesis in Escherichia coliCritical amino acids in Escherichia coli UmuC responsible for sugar discrimination and base-substitution fidelity.Simple and efficient purification of Escherichia coli DNA polymerase V: cofactor requirements for optimal activity and processivity in vitro.Multiple strategies for translesion synthesis in bacteriaChronology in lesion tolerance gives priority to genetic variability.Characterization of Escherichia coli UmuC active-site loops identifies variants that confer UV hypersensitivity.Processing closely spaced lesions during Nucleotide Excision Repair triggers mutagenesis in E. coli.A defect in homologous recombination leads to increased translesion synthesis in E. coli.Architecture of y-family DNA polymerases relevant to translesion DNA synthesis as revealed in structural and molecular modeling studies.Structural model of the Y-Family DNA polymerase V/RecA mutasome.Chronological Switch from Translesion Synthesis to Homology-Dependent Gap Repair
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Biochemical basis for the essential genetic requirements of RecA and the beta-clamp in Pol V activation.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 19 August 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Biochemical basis for the esse ...... eta-clamp in Pol V activation.
@en
Biochemical basis for the esse ...... eta-clamp in Pol V activation.
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type
label
Biochemical basis for the esse ...... eta-clamp in Pol V activation.
@en
Biochemical basis for the esse ...... eta-clamp in Pol V activation.
@nl
prefLabel
Biochemical basis for the esse ...... eta-clamp in Pol V activation.
@en
Biochemical basis for the esse ...... eta-clamp in Pol V activation.
@nl
P2860
P356
P1476
Biochemical basis for the esse ...... eta-clamp in Pol V activation.
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P2093
Robert P Fuchs
Shingo Fujii
P2860
P304
14825-14830
P356
10.1073/PNAS.0905855106
P407
P577
2009-08-19T00:00:00Z