Endothelin antagonism in experimental hepatic fibrosis. Implications for endothelin in the pathogenesis of wound healing.
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Hepatoprotective and Anti-fibrotic Agents: It's Time to Take the Next StepMyofibroblasts: trust your heart and let fate decide.Preproendothelin-1 expression is negatively regulated by IFNγ during hepatic stellate cell activationHepatic stellate cells: protean, multifunctional, and enigmatic cells of the liverRole of Chymase in the Development of Liver Cirrhosis and Its Complications: Experimental and Human DataEndothelin antagonism in portal hypertensive mice: implications for endothelin receptor-specific signaling in liver disease.Endothelin-1 suppresses plasma membrane Ca++-ATPase, concomitant with contraction of hepatic sinusoidal endothelial fenestraeCellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.Molecular mechanism of the reversibility of hepatic fibrosis: with special reference to the role of matrix metalloproteinases.A cytokine reborn? Endothelin-1 in pulmonary inflammation and fibrosis.Tumor necrosis factor α stimulates endothelin-1 synthesis in rat hepatic stellate cells in hepatic wound healing through a novel IKK/JNK pathway.The function of integrin-linked kinase in normal and activated stellate cells: implications for fibrogenesis in wound healingAssociation of age-dependent liver injury and fibrosis with immune cell populations.Role of myofibroblasts at the invasion front.Role of endothelin-1 in acute lung injury.Prevention of cultured rat stellate cell transformation and endothelin-B receptor upregulation by retinoic acid.Adiponectin regulation of stellate cell activation via PPARγ-dependent and -independent mechanisms.Pigment epithelium-derived factor 34-mer peptide prevents liver fibrosis and hepatic stellate cell activation through down-regulation of the PDGF receptor.Role of endothelins in animal models of hypertension: focus on cardiovascular protection.Role of tissue stroma in cancer cell invasion.Regulator of G-protein signaling-5 is a marker of hepatic stellate cells and expression mediates response to liver injuryEndothelin receptor antagonist TAK-044 arrests and reverses the development of carbon tetrachloride induced cirrhosis in rats.Endothelin-1 stimulates contraction and migration of rat pancreatic stellate cells.Pancreatic secretory trypsin inhibitor I reduces the severity of chronic pancreatitis in mice overexpressing interleukin-1β in the pancreas.Cell and molecular regulation of endothelin-1 production during hepatic wound healing.Understanding the mechanism of hepatic fibrosis and potential therapeutic approachesThe role of endothelin-1 in myocarditis and inflammatory cardiomyopathy: old lessons and new insights.Sarcomeric gene expression and contractility in myofibroblasts.Targeting the stromal fibroblasts: a novel approach to melanoma therapy.Divergent transforming growth factor-beta signaling in hepatic stellate cells after liver injury: functional effects on ECE-1 regulationKnockout of endothelin type B receptor signaling attenuates bleomycin-induced skin sclerosis in miceCurrent and future anti-fibrotic therapies for chronic liver disease.Advances in antifibrotic therapy.Cardiac myofibroblasts isolated from the site of myocardial infarction express endothelin de novo.At the heart of tissue: endothelin system and end-organ damage.Endothelin and hepatic wound healing.Translating an understanding of the pathogenesis of hepatic fibrosis to novel therapiesHydroxyurea therapy for priapism prevention and erectile function recovery in sickle cell disease: a case report and review of the literature.Endothelin-1 enhances fibrogenic gene expression, but does not promote DNA synthesis or apoptosis in hepatic stellate cells.Protection against chronic pancreatitis and pancreatic fibrosis in mice overexpressing pancreatic secretory trypsin inhibitor.
P2860
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P2860
Endothelin antagonism in experimental hepatic fibrosis. Implications for endothelin in the pathogenesis of wound healing.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Endothelin antagonism in exper ...... pathogenesis of wound healing.
@en
Endothelin antagonism in exper ...... pathogenesis of wound healing.
@nl
type
label
Endothelin antagonism in exper ...... pathogenesis of wound healing.
@en
Endothelin antagonism in exper ...... pathogenesis of wound healing.
@nl
prefLabel
Endothelin antagonism in exper ...... pathogenesis of wound healing.
@en
Endothelin antagonism in exper ...... pathogenesis of wound healing.
@nl
P2860
P356
P1476
Endothelin antagonism in exper ...... pathogenesis of wound healing.
@en
P2093
P2860
P304
P356
10.1172/JCI118925
P407
P577
1996-09-01T00:00:00Z