Timing and tuning of CD27-CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology.
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Th1 and Th17 Cells in Tuberculosis: Protection, Pathology, and BiomarkersRole of Tumor Necrosis Factor Superfamily in Neuroinflammation and AutoimmunityMolecular mechanisms of T cell co-stimulation and co-inhibitionThe role of costimulatory receptors of the tumour necrosis factor receptor family in atherosclerosisTargeting the T-cell co-stimulatory CD27/CD70 pathway in cancer immunotherapy: rationale and potentialAcute Virus Control Mediated by Licensed NK Cells Sets Primary CD8+ T Cell Dependence on CD27 Costimulation.CD27 stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12-mediated loss of CD8(+) T cell memory in the absence of CD4(+) T cell help.Effects of CD70 and CD11a in immune thrombocytopenia patients.Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8(+) T cell responses to influenzaSoluble CD27-pool in humans may contribute to T cell activation and tumor immunity.Tumour necrosis factor superfamily members in the pathogenesis of inflammatory bowel diseaseDifferential mechanisms of memory CD8 T cell maintenance by individual myeloid cell types.Mechanisms of costimulation.TGF-β upregulates CD70 expression and induces exhaustion of effector memory T cells in B-cell non-Hodgkin's lymphoma.Occupational exposure to trichloroethylene is associated with a decline in lymphocyte subsets and soluble CD27 and CD30 markersExome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients.Mtb-specific CD27low CD4 T cells as markers of lung tissue destruction during pulmonary tuberculosis in humans.Tumor antigen-dependent and tumor antigen-independent activation of antitumor activity in T cells by a bispecific antibody-modified tumor vaccine.Identification of cytolytic CD161- CD56+ regulatory CD8 T cells in human peripheral bloodThe glucocorticoid-induced TNF receptor family-related protein (GITR) is critical to the development of acute pancreatitis in mice.Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathwayReduced naive CD4 T cell numbers and impaired induction of CD27 in response to T cell receptor stimulation reflect a state of immune activation in chronic hepatitis C virus infectionT cells redirected against CD70 for the immunotherapy of CD70-positive malignanciesEnhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection.Human CD38hiCD138⁺ plasma cells can be generated in vitro from CD40-activated switched-memory B lymphocytesExpression of the immune regulation antigen CD70 in osteosarcoma.CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progressionIntrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia.TNF superfamily in inflammatory disease: translating basic insights.Melanoma Expressed-CD70 Is Regulated by RhoA and MAPK Pathways without Affecting Vemurafenib Treatment Activity.Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancerNaïve and memory B cells in the rhesus macaque can be differentiated by surface expression of CD27 and have differential responses to CD40 ligation.Regulation of the PKCθ-NF-κB Axis in T Lymphocytes by the Tumor Necrosis Factor Receptor Family Member OX40Interaction of tumor cells with infiltrating lymphocytes via CD70 and CD27 in clear cell renal cell carcinoma.Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy.Distinctive features of the differentiated phenotype and infiltration of tumor-reactive lymphocytes in clear cell renal cell carcinomaT cell vaccinology: exploring the known unknowns.CD70 deficiency impairs effector CD8 T cell generation and viral clearance but is dispensable for the recall response to lymphocytic choriomeningitis virus.T Cell Vaccinology: Beyond the Reflection of Infectious ResponsesCD27 expression discriminates porcine T helper cells with functionally distinct properties.
P2860
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P2860
Timing and tuning of CD27-CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Timing and tuning of CD27-CD70 ...... responses and immunopathology.
@en
Timing and tuning of CD27-CD70 ...... responses and immunopathology.
@nl
type
label
Timing and tuning of CD27-CD70 ...... responses and immunopathology.
@en
Timing and tuning of CD27-CD70 ...... responses and immunopathology.
@nl
prefLabel
Timing and tuning of CD27-CD70 ...... responses and immunopathology.
@en
Timing and tuning of CD27-CD70 ...... responses and immunopathology.
@nl
P2093
P1476
Timing and tuning of CD27-CD70 ...... responses and immunopathology.
@en
P2093
Klaas P J M van Gisbergen
René A W van Lier
Ronald W van Olffen
P304
P356
10.1111/J.1600-065X.2009.00774.X
P577
2009-05-01T00:00:00Z