Arsenite binding-induced zinc loss from PARP-1 is equivalent to zinc deficiency in reducing PARP-1 activity, leading to inhibition of DNA repair.
about
Arsenic Disruption of DNA Damage Responses-Potential Role in Carcinogenesis and ChemotherapyArsenite selectively inhibits mouse bone marrow lymphoid progenitor cell development in vivo and in vitro and suppresses humoral immunity in vivoInorganic Arsenic-induced cellular transformation is coupled with genome wide changes in chromatin structure, transcriptome and splicing patternsKinetics and thermodynamics of zinc(II) and arsenic(III) binding to XPA and PARP-1 zinc finger peptidesInhibition of poly(ADP-ribose)polymerase-1 and DNA repair by uranium.Selective Sensitization of Zinc Finger Protein Oxidation by Reactive Oxygen Species through Arsenic Binding.Differential sensitivities of cellular XPA and PARP-1 to arsenite inhibition and zinc rescue.Environmentally Relevant Concentrations of Arsenite Induce Dose-Dependent Differential Genotoxicity Through Poly(ADP-Ribose) Polymerase Inhibition and Oxidative Stress in Mouse Thymus Cells.Arsenite Targets the Zinc Finger Domains of Tet Proteins and Inhibits Tet-Mediated Oxidation of 5-Methylcytosine.Arsenite Disrupts Zinc-Dependent TGFβ2-SMAD Activity During Murine Cardiac Progenitor Cell DifferentiationS-nitrosation on zinc finger motif of PARP-1 as a mechanism of DNA repair inhibition by arsenite.Differential binding of monomethylarsonous acid compared to arsenite and arsenic trioxide with zinc finger peptides and proteins.Efflux Transporters Regulate Arsenite Induced Genotoxicity in Double Negative and Double Positive T Cells.A comprehensive look of poly(ADP-ribose) polymerase inhibition strategies and future directions for cancer therapy.Zinc Transport Differs in Rat Spermatogenic Cell Types and Is Affected by Treatment with Cyclophosphamide.Zinc enhances the number of regulatory T cells in allergen-stimulated cells from atopic subjects.Differential sensitivities of bone marrow, spleen and thymus to genotoxicity induced by environmentally relevant concentrations of arsenite.Detoxification effects of phytonutrients against environmental toxicants and sharing of clinical experience on practical applications.
P2860
Q26781256-58E2FB1F-DD16-4F08-B038-835CEFC442F6Q28383651-489B27B1-90AB-4FDF-A8D8-0013ED890D96Q28390396-74A47BEE-9CDA-4BE3-BDA1-699B4F09864FQ28393344-F2034ECE-45C4-4A6A-9FEB-969AD26D39D3Q35857830-2D9643EE-3BD9-497B-9DA7-79F8AEF7EEA4Q35883788-C7FE15B7-E4D9-4360-9198-EBE310FFDF8DQ36383755-9F7AAF48-24CB-4DCD-9241-E22871FB9DD4Q36468922-1BA0DDD6-6289-43A9-BCE2-AB4D59ED05ADQ36667415-422D8D90-1B75-4731-99E6-2C703C2A735CQ37228117-5D7133B0-642E-40FC-94D6-EB0AD9BC53E0Q37697027-F3AB6DBD-9B3D-48FB-B013-8389A11BD082Q37721696-E7286473-382E-4DE5-8CE7-D54837CE0B5DQ38704863-8C14CF1B-19A9-439F-8475-46DD4DC91B51Q38780396-12E13676-E018-4309-925A-F9D218D2008AQ39696310-C85C08AD-5A71-4ADF-ABA1-CD101DF086D9Q40295262-CBCB5D00-0908-4088-9243-9C142A179E01Q46473039-4D527B0D-A036-4F05-905E-82CB92319FD6Q50247591-3C31E5F8-3229-4527-89E1-B1926556D9F9
P2860
Arsenite binding-induced zinc loss from PARP-1 is equivalent to zinc deficiency in reducing PARP-1 activity, leading to inhibition of DNA repair.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
Arsenite binding-induced zinc ...... g to inhibition of DNA repair.
@en
Arsenite binding-induced zinc ...... g to inhibition of DNA repair.
@nl
type
label
Arsenite binding-induced zinc ...... g to inhibition of DNA repair.
@en
Arsenite binding-induced zinc ...... g to inhibition of DNA repair.
@nl
prefLabel
Arsenite binding-induced zinc ...... g to inhibition of DNA repair.
@en
Arsenite binding-induced zinc ...... g to inhibition of DNA repair.
@nl
P2093
P2860
P1476
Arsenite binding-induced zinc ...... g to inhibition of DNA repair.
@en
P2093
Ke Jian Liu
Laurie G Hudson
Wenlan Liu
P2860
P304
P356
10.1016/J.TAAP.2013.11.010
P577
2013-11-22T00:00:00Z