Potentiation of antiherpetic activity of acyclovir by ribonucleotide reductase inhibition
about
Antiviral activity of a selective ribonucleotide reductase inhibitor against acyclovir-resistant herpes simplex virus type 1 in vivoDelayed treatment with combinations of antiviral drugs in mice infected with herpes simplex virus and application of the median effect method of analysis2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (A1110U), a potent inactivator of ribonucleotide reductases of herpes simplex and varicella-zoster viruses and a potentiator of acyclovir.Protein-protein interactions as targets for antiviral chemotherapy.Effects of ribonucleotide reductase inhibition on pyrimidine deoxynucleotide metabolism in acyclovir-treated cells infected with herpes simplex virus type 1Synergistic therapy by acyclovir and A1110U for mice orofacially infected with herpes simplex viruses.Specific inhibition of herpes virus replication by receptor-mediated entry of an antiviral peptide linked to Escherichia coli enterotoxin B subunit.Strategic design and three-dimensional analysis of antiviral drug combinations.Inactivators of herpes simplex virus ribonucleotide reductase: hematological profiles and in vivo potentiation of the antiviral activity of acyclovirDeletion of the varicella-zoster virus large subunit of ribonucleotide reductase impairs growth of virus in vitro.Ribonucleotide reductase inhibitors hydroxyurea, didox, and trimidox inhibit human cytomegalovirus replication in vitro and synergize with ganciclovir.Resveratrol, sirtuins, and viruses.Chemotherapy of herpesvirus infections.Disruption of herpes simplex virus ribonucleotide reductase quaternary structure by peptide inhibitors as a novel approach to antiviral therapy.Susceptibility of a herpes simplex virus ribonucleotide reductase null mutant to deoxyribonucleosides and antiviral nucleoside analogs.Emerging therapeutic targets in antiviral and anticancer therapy: a role for ribonucleotide reductase
P2860
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P2860
Potentiation of antiherpetic activity of acyclovir by ribonucleotide reductase inhibition
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 1985
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Potentiation of antiherpetic activity of acyclovir by ribonucleotide reductase inhibition
@en
Potentiation of antiherpetic a ...... cleotide reductase inhibition.
@nl
type
label
Potentiation of antiherpetic activity of acyclovir by ribonucleotide reductase inhibition
@en
Potentiation of antiherpetic a ...... cleotide reductase inhibition.
@nl
prefLabel
Potentiation of antiherpetic activity of acyclovir by ribonucleotide reductase inhibition
@en
Potentiation of antiherpetic a ...... cleotide reductase inhibition.
@nl
P2093
P2860
P356
P1476
Potentiation of antiherpetic activity of acyclovir by ribonucleotide reductase inhibition
@en
P2093
Averett DR
Morrison RW Jr
St Clair MH
P2860
P304
P356
10.1073/PNAS.82.12.4254
P407
P577
1985-06-01T00:00:00Z