Teaching an old dogma new tricks: twenty years of Shc adaptor signalling.
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Nitric oxide, oxidative stress, and p66Shc interplay in diabetic endothelial dysfunctionUrokinase-type plasminogen activator receptor (uPAR) ligation induces a raft-localized integrin signaling switch that mediates the hypermotile phenotype of fibrotic fibroblastsAdapter protein Shc regulates Janus kinase 3 phosphorylationEvidence for a novel antioxidant function and isoform-specific regulation of the human p66Shc gene.The influence of Shc proteins on life span in mice.Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulationMet receptor-induced Grb2 or Shc signals both promote transformation of intestinal epithelial cells, albeit they are required for distinct oncogenic functions.ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation.EGF-receptor specificity for phosphotyrosine-primed substrates provides signal integration with SrcThe ShcD signaling adaptor facilitates ligand-independent phosphorylation of the EGF receptor.DNA methylation and substance-use risk: a prospective, genome-wide study spanning gestation to adolescence.Understanding and applying tyrosine biochemical diversity.Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors.Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy CellsSHIP2: Structure, Function and Inhibition.PI3 kinase is indispensable for oncogenic transformation by the V560D mutant of c-Kit in a kinase-independent manner.Up-regulation of N-cadherin by Collagen I-activated Discoidin Domain Receptor 1 in Pancreatic Cancer Requires the Adaptor Molecule Shc1.The Src homology and collagen A (ShcA) adaptor protein is required for the spatial organization of the costamere/Z-disk network during heart development.Role of herpes simplex virus VP11/12 tyrosine-based motifs in binding and activation of the Src family kinase Lck and recruitment of p85, Grb2, and Shc.The ShcD phosphotyrosine adaptor subverts canonical EGF receptor trafficking.Non-canonical dynamic mechanisms of interaction between the p66Shc protein and Met receptorMeasuring p66Shc Signaling Pathway Activation and Mitochondrial Translocation in Cultured Cells.Regulation of insulin-like growth factor receptors by Ubiquilin1.ShcA Adaptor Protein Promotes Nephrin Endocytosis and Is Upregulated in Proteinuric Nephropathies.Acute Ethanol Increases IGF-I-Induced Phosphorylation of ERKs by Enhancing Recruitment of p52-Shc to the Grb2/Shc Complex.[Control of insulin signalisation and action by the Grb14 protein].Loss of the adaptor protein ShcA in endothelial cells protects against monocyte macrophage adhesion, LDL-oxydation, and atherosclerotic lesion formation.
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Teaching an old dogma new tricks: twenty years of Shc adaptor signalling.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Teaching an old dogma new tricks: twenty years of Shc adaptor signalling.
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type
label
Teaching an old dogma new tricks: twenty years of Shc adaptor signalling.
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prefLabel
Teaching an old dogma new tricks: twenty years of Shc adaptor signalling.
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P2860
P356
P1433
P1476
Teaching an old dogma new tricks: twenty years of Shc adaptor signalling
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P2093
Nina Jones
P2860
P356
10.1042/BJ20120769
P407
P577
2012-10-01T00:00:00Z