Involvement of mixed lineage kinase 3 in cancer. - Wikidata - awgldk - TriplyDB

Involvement of mixed lineage kinase 3 in cancer.

Involvement of mixed lineage kinase 3 in cancer.

http://www.wikidata.org/entity/Q38102775

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MLK3 phophorylates AMPK independently of LKB1.Decrement of miR-199a-5p contributes to the tumorigenesis of bladder urothelial carcinoma by regulating MLK3/NF-κB pathway

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Involvement of mixed lineage kinase 3 in cancer.

http://www.wikidata.org/entity/Q38102775

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article científic

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artikel ilmiah

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Involvement of mixed lineage kinase 3 in cancer.

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Involvement of mixed lineage kinase 3 in cancer.

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Involvement of mixed lineage kinase 3 in cancer.

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Canadian Journal of Physiology and Pharmacology

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Involvement of mixed lineage kinase 3 in cancer.

@en

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Deborah N Chadee

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Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3

Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation

The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation

MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation

Regulation of mixed lineage kinase 3 is required for Neurofibromatosis-2-mediated growth suppression in human cancer

The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

Inflammation and cancer

Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: optimization, mixed-lineage kinase 1 crystallography, and oral in vivo activity in 1-methyl-4-phenyltetrahydropyridine models

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

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268-274

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scholarly article

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10.1139/CJPP-2012-0258

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4

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91

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2012-12-19T00:00:00Z

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23627838

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