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Actin-Dependent Alterations of Dendritic Spine Morphology in ShankopathiesAutistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2Development of novel Zn2+ loaded nanoparticles designed for cell-type targeted drug release in CNS neurons: in vitro evidencesZinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3.Behavioral impairments in animal models for zinc deficiency.The Shank3 Interaction Partner ProSAPiP1 Regulates Postsynaptic SPAR Levels and the Maturation of Dendritic Spines in Hippocampal Neurons.Zinc in gut-brain interaction in autism and neurological disorders.Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturationEffects of trace metal profiles characteristic for autism on synapses in cultured neuronsAmyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold.N-Cadherin-mediated cell adhesion is regulated by extracellular Zn(2+).Brain-Delivery of Zinc-Ions as Potential Treatment for Neurological Diseases: Mini Review.Nanoparticle transport across the blood brain barrier.Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling.Small-molecule XIAP inhibitors enhance gamma-irradiation-induced apoptosis in glioblastoma.The Nedd4-binding protein 3 (N4BP3) is crucial for axonal and dendritic branching in developing neurons.Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies.A role for synaptic zinc in ProSAP/Shank PSD scaffold malformation in autism spectrum disorders.Characterization of biometal profiles in neurological disorders.Emerging Use of Nanotechnology in the Treatment of Neurological Disorders.Novel Curcumin loaded nanoparticles engineered for Blood-Brain Barrier crossing and able to disrupt Abeta aggregates.Insight on the fate of CNS-targeted nanoparticles. Part II: Intercellular neuronal cell-to-cell transport.Extracerebral Dysfunction in Animal Models of Autism Spectrum Disorder.Cellular Zinc Homeostasis Contributes to Neuronal Differentiation in Human Induced Pluripotent Stem Cells.Molecular and Cellular Mechanisms of SynaptopathiesCharacterization of zinc amino acid complexes for zinc delivery in vitro using Caco-2 cells and enterocytes from hiPSC.Loss of COMMD1 and copper overload disrupt zinc homeostasis and influence an autism-associated pathway at glutamatergic synapses.Synaptogenesis of hippocampal neurons in primary cell culture.The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation.De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability.Efficient targeting of proteins to post-synaptic densities of excitatory synapses using a novel pSDTarget vector system.Zinc Binding to S100B Affords Regulation of Trace Metal Homeostasis and Excitotoxicity in the Brain.Activity and circadian rhythm influence synaptic Shank3 protein levels in mice.Reduced plaque size and inflammation in the APP23 mouse model for Alzheimer's disease after chronic application of polymeric nanoparticles for CNS targeted zinc delivery.Application of Polymeric Nanoparticles for CNS Targeted Zinc Delivery In Vivo.Insight on the fate of CNS-targeted nanoparticles. Part I: Rab5-dependent cell-specific uptake and distribution.Hybrid nanoparticles as a new technological approach to enhance the delivery of cholesterol into the brain.Prospects of Zinc Supplementation in Autism Spectrum Disorders and Shankopathies Such as Phelan McDermid Syndrome.EXPLOITING THE VERSATILITY OF CHOLESTEROL IN NANOPARTICLES FORMULATIONRare Feeding Behavior of Great-Tailed Grackles (Quiscalus mexicanus) in the Extreme Habitat of Death Valley~!2010-01-08~!2010-03-08~!2010-05-21~!
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description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
Andreas M. Grabrucker
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Andreas M. Grabrucker
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Andreas M. Grabrucker
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Andreas M. Grabrucker
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type
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Andreas M. Grabrucker
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Andreas M. Grabrucker
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Andreas M. Grabrucker
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Andreas M. Grabrucker
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altLabel
Andreas Martin Grabrucker
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Andreas M. Grabrucker
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Andreas M. Grabrucker
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Andreas M. Grabrucker
@es
Andreas M. Grabrucker
@nl
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P1153
26654880700
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0000-0003-0005-4810