Methylation of CpG dinucleotides in the lacI gene of the Big Blue transgenic mouse.

Methylation of CpG dinucleotides in the lacI gene of the Big Blue transgenic mouse.

Item
http://www.wikidata.org/entity/Q38330786
Mutation frequency and specificity with age in liver, bladder and brain of lacI transgenic miceTransitions at CpG dinucleotides, geographic clustering of TP53 mutations and food availability patterns in colorectal cancerSpontaneous hepatocellular carcinoma is reduced in transgenic mice overexpressing human O6- methylguanine-DNA methyltransferase.Through a glass, darkly: reflections of mutation from lacI transgenic mice.Treatment and sampling protocols for transgenic mutation assays.Evidence for mutation showers.Rev1 promotes replication through UV lesions in conjunction with DNA polymerases η, ι, and κ but not DNA polymerase ζEpigenetic regulation of genetic integrity is reprogrammed during cloning.Comparative genomic study reveals a transition from TA richness in invertebrates to GC richness in vertebrates at CpG flanking sites: an indication for context-dependent mutagenicity of methylated CpG sitesRelatively high rates of G:C → A:T transitions at CpG sites were observed in certain epithelial tissues including pancreas and submaxillary gland of adult big blue® mice.Distribution of spontaneous CpG-associated G:C --> A:T mutations in the lacZ gene of Muta mice: effects of CpG methylation, the sequence context of CpG sites, and severity of mutations on the activity of the lacZ gene product.A human cancer-associated truncation of MBD4 causes dominant negative impairment of DNA repair in colon cancer cells.Characterization of mutant spectra generated by a forward mutational assay for gene A of Phi X174 from ENU-treated transgenic mouse embryonic cell line PX-2.Re-evaluation of the Big Blue® mouse assay of propiconazole suggests lack of mutagenicity.
P2860

Methylation of CpG dinucleotides in the lacI gene of the Big Blue transgenic mouse.

Item
http://www.wikidata.org/entity/Q38330786
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Methylation of CpG dinucleotides in the lacI gene of the Big Blue transgenic mouse.
@en
type
label
Methylation of CpG dinucleotides in the lacI gene of the Big Blue transgenic mouse.
@en
prefLabel
Methylation of CpG dinucleotides in the lacI gene of the Big Blue transgenic mouse.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Methylation of CpG dinucleotides in the lacI gene of the Big Blue transgenic mouse.
@en
P2093
P304
P31
P356
10.1016/S1383-5718(98)00147-8
P407
P433
P478
P577
P698