Suppression of transcription factor PDX-1/IPF1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells. - Wikidata - awgldk - TriplyDB

Suppression of transcription factor PDX-1/IPF1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells.

Suppression of transcription factor PDX-1/IPF1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells.

http://www.wikidata.org/entity/Q38342794

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Exendin-4 differentiation of a human pancreatic duct cell line into endocrine cells: involvement of PDX-1 and HNF3beta transcription factors Increased islet apoptosis in Pdx1+/- mice Mechanisms of action of glucagon-like peptide 1 in the pancreas Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes.A multi-parameter, high-content, high-throughput screening platform to identify natural compounds that modulate insulin and Pdx1 expression.Neutralizing interleukin-1beta (IL-1beta) induces beta-cell survival by maintaining PDX1 protein nuclear localization.Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus.Hepatocyte nuclear factor-1alpha inhibits insulin promoter factor 1-dependent transactivation of the human insulin gene.Glucose stimulates translocation of the homeodomain transcription factor PDX1 from the cytoplasm to the nucleus in pancreatic beta-cells.

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P2860

Suppression of transcription factor PDX-1/IPF1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells.

http://www.wikidata.org/entity/Q38342794

description

1997 nî lūn-bûn

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1997年の論文

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年學術文章

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1997年學術文章

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1997年學術文章

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name

Suppression of transcription f ...... in insulin mRNA in MIN6 cells.

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Suppression of transcription f ...... in insulin mRNA in MIN6 cells.

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Suppression of transcription f ...... in insulin mRNA in MIN6 cells.

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Journal of Clinical Investigation

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Suppression of transcription f ...... in insulin mRNA in MIN6 cells

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Fujitani Y

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Kajimoto Y

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Kaneto H

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Matsuoka T

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Yamasaki Y

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P2860

Involvement of the homeodomain-containing transcription factor PDX-1 in islet amyloid polypeptide gene transcription

Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11

Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone

Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein

Insulin-promoter-factor 1 is required for pancreas development in mice

A beta-cell-specific protein binds to the two major regulatory sequences of the insulin gene enhancer

Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression

Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein.

Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells.

Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations.

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1840-1846

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10.1172/JCI119712

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7

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100

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Hirotaka Watada

Jun-ichi Miyazaki

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1997-10-01T00:00:00Z

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13910404

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9312185

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508370

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