MKP-1 switches arginine metabolism from nitric oxide synthase to arginase following endotoxin challenge.
about
G2A deficiency in mice promotes macrophage activation and atherosclerosis.Increased arginase II activity contributes to endothelial dysfunction through endothelial nitric oxide synthase uncoupling in aged miceIs the urea cycle involved in Alzheimer's disease?Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.Redox regulation of MAPK phosphatase 1 controls monocyte migration and macrophage recruitment.MAP kinase phosphatase-2 plays a critical role in response to infection by Leishmania mexicana.Mice deficient in Mkp-1 develop more severe pulmonary hypertension and greater lung protein levels of arginase in response to chronic hypoxia.Increased inflammation, impaired bacterial clearance, and metabolic disruption after gram-negative sepsis in Mkp-1-deficient miceNitric oxide synthase inhibition enhances the antitumor effect of radiation in the treatment of squamous carcinoma xenografts.Asymmetric dimethylarginine does not inhibit arginase activity and is pro-proliferative in pulmonary endothelial cells.Piceatannol-3'-O-beta-D-glucopyranoside as an active component of rhubarb activates endothelial nitric oxide synthase through inhibition of arginase activity.Arginase I gene single-nucleotide polymorphism is associated with decreased risk of pulmonary hypertension in bronchopulmonary dysplasia.OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling.Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.Nitric oxide suppression of cellular proliferation depends on cationic amino acid transporter activity in cytokine-stimulated pulmonary endothelial cellsExtracellular signal-regulated kinase mediates expression of arginase II but not inducible nitric-oxide synthase in lipopolysaccharide-stimulated macrophages.Arginase Inhibition by Ethylacetate Extract of Caesalpinia sappan Lignum Contributes to Activation of Endothelial Nitric Oxide Synthase.Endothelial arginase II and atherosclerosis.Mitogen-activated protein kinase phosphatase (MKP)-1 in immunology, physiology, and disease.Korean red ginseng inhibits arginase and contributes to endotheliumdependent vasorelaxation through endothelial nitric oxide synthase coupling.Cytokine-induced arginase activity in pulmonary endothelial cells is dependent on Src family tyrosine kinase activity.Histone H3 as a novel substrate for MAP kinase phosphatase-1.Quantitative RT-PCR comparison of the urea and nitric oxide cycle gene transcripts in adult human tissues.Arginase as a potential target in the treatment of cardiovascular disease: reversal of arginine steal?Reactive nitrogen species and hydrogen sulfide as regulators of protein tyrosine phosphatase activity.An arginase-1 SNP that protects against the development of pulmonary hypertension in bronchopulmonary dysplasia enhances NO-mediated apoptosis in lymphocytes.A new metabolomic assay to examine inflammation and redox pathways following LPS challenge.Metabolomics of cerebrospinal fluid reveals changes in the central nervous system metabolism in a rat model of multiple sclerosis.Arginase Structure and Inhibition: Catalytic Site Plasticity Reveals New Modulation Possibilities.Sequential expression of macrophage anti-microbial/inflammatory and wound healing markers following innate, alternative and classical activation.Deficiency of mitogen-activated protein kinase phosphatase-1 results in iNOS-mediated hypotension in response to low-dose endotoxin.Hypoxic proliferation requires EGFR-mediated ERK activation in human pulmonary microvascular endothelial cells.
P2860
Q24643942-A1497D33-7398-428C-9CE3-B6572EBEFE0DQ28390561-99C2CABE-AAC3-467D-B228-E3A527FE1148Q30433662-6CD1CFE9-B75B-456E-82B2-E718B59E15C7Q30436091-3090FA7F-6DD3-4523-A813-90AFE13ADC26Q30525793-00E824C8-F682-4A64-8A9E-DCE314B4FE7FQ33750045-D971A6A8-C3A8-497B-ABD2-E0F4E849197EQ33840756-56A52D34-CA8D-49F2-83C1-D9D1FC085179Q33899125-90DA1A41-24EB-44DD-AF28-B36AF821DA1CQ33925368-E8F3CBA0-3B97-4365-A071-814A91CEE10AQ33934764-B453F0C5-F8A5-4D22-B768-D54954E0BDE0Q34029838-D95CEA74-8DA0-48D4-A02F-666F3A1A2FA9Q34270453-3926B3C1-DC76-4AFF-917D-FA4403D5C068Q34543359-CE94CF5B-0955-4903-AF16-B4BA2A732E18Q34677714-D7EECFF3-CFD7-454F-98B5-C83D892A088FQ34784965-B63C2904-D0A8-472F-ACF1-47564199AFC3Q35002841-9F7998B4-6EB9-46A4-B0D2-FFB3C1409A07Q35158889-94DABFE1-F9B8-4DA1-B7F5-D7AB71844B2BQ35161493-AC805174-67AF-4619-BCF1-02889EB330A4Q36301783-35AFB8C0-CD2E-42C8-B4B0-0100C0E30929Q36861288-D52B97B9-F99B-4D1F-BBB0-E9BEB1813EF6Q36956205-4FBCEC17-E096-45AE-9C62-C57E9A5F8038Q37100021-CBE98E79-3BE7-419B-927D-DAA42DED2ACFQ37187846-97574523-66CF-40FD-871B-99161C0A701AQ38082329-56174C38-D34F-4E8A-9131-1B3A7E05BA5AQ38170414-E0596FE0-3D18-4E6B-B59A-47B638FD31ACQ39147384-592A1012-684B-4DFB-B3F8-7F47CC161447Q39266063-E7E134E0-3C9B-4146-ABF3-7A7F5A757193Q41952903-3A1C8865-8EE6-4810-86E9-0F386E2504A3Q42670315-5AD36D80-9101-4ED4-9692-025CBA95E0DDQ44240692-179EC474-6400-433B-A858-5880AED058C2Q46748396-1A59B4B8-D523-40C3-A0A9-ADC55D507044Q47976677-B7B1908E-35CE-45A8-A82B-79ECF41D1F31
P2860
MKP-1 switches arginine metabolism from nitric oxide synthase to arginase following endotoxin challenge.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
MKP-1 switches arginine metabo ...... following endotoxin challenge.
@en
type
label
MKP-1 switches arginine metabo ...... following endotoxin challenge.
@en
prefLabel
MKP-1 switches arginine metabo ...... following endotoxin challenge.
@en
P2093
P2860
P1476
MKP-1 switches arginine metabo ...... following endotoxin challenge
@en
P2093
B Keith English
Dionna M Hatch
Leif D Nelin
Louis G Chicoine
Xianxi Wang
P2860
P304
P356
10.1152/AJPCELL.00137.2006
P577
2007-04-18T00:00:00Z