Developing predictive assays: the phenotypic screening "rule of 3".
about
The Power of Sophisticated Phenotypic Screening and Modern Mechanism-of-Action Methods.Real-Time Biological Annotation of Synthetic Compounds.Phenotypic Assessment and the Discovery of Topiramate.Small-molecule phenotypic screening with stem cells.Biophysics: for HTS hit validation, chemical lead optimization, and beyond.Novel drug discovery for Chagas disease.Alternative Models of Developmental and Reproductive Toxicity in Pharmaceutical Risk Assessment and the 3Rs.Next-generation phenotypic screening.High content analysis in amyotrophic lateral sclerosis.Induced pluripotent stem cell technology: a decade of progress.Perfused Three-dimensional Organotypic Culture of Human Cancer Cells for Therapeutic Evaluation.Progress does not just come in giant leaps: adapting techniques for the study of inflammation to novel applications.Development of the Digital Arthritis Index, a Novel Metric to Measure Disease Parameters in a Rat Model of Rheumatoid Arthritis.Application of a phenotypic drug discovery strategy to identify biological and chemical starting points for inhibition of TSLP production in lung epithelial cells.Translating Knowledge Into Therapy for Acute Kidney Injury.Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen.Label-Free Dynamic Mass Redistribution and Bio-Impedance Methods for Drug Discovery.Inflammatory pathway network-based drug repositioning and molecular phenomics.Improved Scalability of Neuron-Based Phenotypic Screening Assays for Therapeutic Discovery in Neuropsychiatric Disorders.Live-single-cell phenotypic cancer biomarkers-future role in precision oncology?An industry perspective on drug target validationDevelopment of a Novel 3D Tumor-tissue Invasion Model for High-throughput, High-content Phenotypic Drug Screening
P2860
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P2860
Developing predictive assays: the phenotypic screening "rule of 3".
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Developing predictive assays: the phenotypic screening "rule of 3".
@en
type
label
Developing predictive assays: the phenotypic screening "rule of 3".
@en
prefLabel
Developing predictive assays: the phenotypic screening "rule of 3".
@en
P2093
P2860
P1476
Developing predictive assays: the phenotypic screening "rule of 3".
@en
P2093
Adam Gilbert
Claire Steppan
Fabien Vincent
Karl Nocka
Linda Kitching
Marie-Claire Peakman
Marko Pregel
Paula Loria
Regis Doyonnas
Robert Stanton
P2860
P304
P356
10.1126/SCITRANSLMED.AAB1201
P407
P577
2015-06-01T00:00:00Z