Overexpression of 14-3-3ζ in cancer cells activates PI3K via binding the p85 regulatory subunit.
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14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2Involvement of 14-3-3 Proteins in Regulating Tumor Progression of Hepatocellular CarcinomaIncreased 14-3-3ζ expression in the multidrug-resistant leukemia cell line HL-60/VCR as compared to the parental line mediates cell growth and apoptosis in part through modification of gene expression14-3-3 zeta as novel molecular target for cancer therapyEstablishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditionsUsing immunomic approach to enhance tumor-associated autoantibody detection in diagnosis of hepatocellular carcinoma.14-3-3ε overexpression contributes to epithelial-mesenchymal transition of hepatocellular carcinoma.Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survivalThe link between the metabolic syndrome and cancer.14-3-3 proteins as potential therapeutic targets.14-3-3 Proteins: diverse functions in cell proliferation and cancer progression.Destabilisation of dimeric 14-3-3 proteins as a novel approach to anti-cancer therapeutics.Quantitative label-free mass spectrometry analysis of formalin-fixed, paraffin-embedded tissue representing the invasive cutaneous malignant melanoma proteome.MEDICI: Mining Essentiality Data to Identify Critical Interactions for Cancer Drug Target Discovery and Development.Altered expression of microRNA-451 in eutopic endometrium of baboons (Papio anubis) with endometriosis.TDRG1 functions in testicular seminoma are dependent on the PI3K/Akt/mTOR signaling pathwayA Cytosolic Multiprotein Complex Containing p85α Is Required for β-Catenin Activation in Colitis and Colitis-associated Cancer.Upregulation of lactate dehydrogenase a by 14-3-3ζ leads to increased glycolysis critical for breast cancer initiation and progression.14-3-3ζ orchestrates mammary tumor onset and progression via miR-221-mediated cell proliferation.miR-22 targets YWHAZ to inhibit metastasis of hepatocellular carcinoma and its down-regulation predicts a poor survival.c-Myc suppresses miR-451⊣YWTAZ/AKT axis via recruiting HDAC3 in acute myeloid leukemia.14-3-3-β and -{varepsilon} contribute to activation of the osmoprotective transcription factor NFAT5 by increasing its protein abundance and its transactivating activity.A single amino acid substitution confers B-cell clonogenic activity to the HIV-1 matrix protein p17.14-3-3ζ up-regulates hypoxia-inducible factor-1α in hepatocellular carcinoma via activation of PI3K/Akt/NF-кB signal transduction pathway.Cytokine-induced macropinocytosis in macrophages is regulated by 14-3-3ζ through its interaction with serine-phosphorylated coronin 1.14-3-3ζ loss impedes oncogene-induced mammary tumorigenesis and metastasis by attenuating oncogenic signaling.14-3-3 Proteins regulate Akt Thr308 phosphorylation in intestinal epithelial cells.Identification of a novel YAP-14-3-3ζ negative feedback loop in gastric cancer.Relationship of 14-3-3zeta (ζ), HIF-1α, and VEGF expression in human brain gliomas.Suppression of 14-3-3ζ in cholangiocarcinoma cells inhibits proliferation through attenuated Akt activity, enhancing chemosensitivity to gemcitabine.14-3-3ζ regulates immune response through Stat3 signaling in oral squamous cell carcinoma.The p85 regulatory subunit of PI3K mediates cAMP-PKA and insulin biological effects on MCF-7 cell growth and motility.Norepinephrine triggers an immediate-early regulatory network response in primary human white adipocytes
P2860
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P2860
Overexpression of 14-3-3ζ in cancer cells activates PI3K via binding the p85 regulatory subunit.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Overexpression of 14-3-3ζ in c ...... ng the p85 regulatory subunit.
@en
type
label
Overexpression of 14-3-3ζ in c ...... ng the p85 regulatory subunit.
@en
prefLabel
Overexpression of 14-3-3ζ in c ...... ng the p85 regulatory subunit.
@en
P2093
P2860
P356
P1433
P1476
Overexpression of 14-3-3ζ in c ...... ng the p85 regulatory subunit.
@en
P2093
S L Wyszomierski
P2860
P2888
P304
P356
10.1038/ONC.2011.284
P407
P577
2011-07-11T00:00:00Z
P5875
P6179
1027088192