Leishmania donovani exploits host deubiquitinating enzyme A20, a negative regulator of TLR signaling, to subvert host immune response.
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Innate immunity against Leishmania infectionsDeubiquitinating enzymes as promising drug targets for infectious diseases.Deception and manipulation: the arms of leishmania, a successful parasiteMicroRNA expression profile in human macrophages in response to Leishmania major infectionA20 is critical for the induction of Pam3CSK4-tolerance in monocytic THP-1 cellsAntileishmanial effect of 18β-glycyrrhetinic acid is mediated by Toll-like receptor-dependent canonical and noncanonical p38 activationRevealing a Novel Otubain-Like Enzyme from Leishmania infantum with Deubiquitinating Activity toward K48-Linked SubstrateLeishmania donovani Exploits Myeloid Cell Leukemia 1 (MCL-1) Protein to Prevent Mitochondria-dependent Host Cell Apoptosis.Antimony-resistant but not antimony-sensitive Leishmania donovani up-regulates host IL-10 to overexpress multidrug-resistant protein 1.Mechanisms of immune evasion in leishmaniasisTRAF molecules in cell signaling and in human diseasesSignaling networks in Leishmania macrophages deciphered through integrated systems biology: a mathematical modeling approach.Increased A20 mRNA Level in Peripheral Blood Mononuclear Cells is Associated With Immune Phases of Patients With Chronic Hepatitis B.The role of vitamin D in the control of Leishmania infection.Leishmania donovani chaperonin 10 regulates parasite internalization and intracellular survival in human macrophages.IRAK-M regulates the inhibition of TLR-mediated macrophage immune response during late in vitro Leishmania donovani infection.Leishmania donovani prevents oxidative burst-mediated apoptosis of host macrophages through selective induction of suppressors of cytokine signaling (SOCS) proteins.Redundant and regulatory roles for Toll-like receptors in Leishmania infection.The role of PD-1 in regulation of macrophage apoptosis and its subversion by Leishmania donovani.Pathogen-induced ubiquitin-editing enzyme A20 bifunctionally shuts off NF-κB and caspase-8-dependent apoptotic cell death.Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to InfectionLeishmania donovani inhibits macrophage apoptosis and pro-inflammatory response through AKT-mediated regulation of β-catenin and FOXO-1Orange-spotted grouper Epinephelus coioides Tak1: molecular identification, expression analysis and functional study.Plasmodium falciparum PfEMP1 Modulates Monocyte/Macrophage Transcription Factor Activation and Cytokine and Chemokine Responses.NF-κB-regulated ubiquitin-editing enzyme A20 paves the way for infection persistency.PDL-1 blockade prevents T cell exhaustion, inhibits autophagy, and promotes clearance of Leishmania donovani.The Toxoplasma gondii ME-49 strain upregulates levels of A20 that inhibit NF-κB activation and promotes apoptosis in human leukaemia T-cell lines.Leishmania guyanensis parasites block the activation of the inflammasome by inhibiting maturation of IL-1β.Leishmania Hijacks Myeloid Cells for Immune Escape.Possible Interrelationship of Inflammatory Cells in Dry Type Cutaneous Leishmaniasis.
P2860
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P2860
Leishmania donovani exploits host deubiquitinating enzyme A20, a negative regulator of TLR signaling, to subvert host immune response.
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2012 nî lūn-bûn
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name
Leishmania donovani exploits h ...... subvert host immune response.
@en
Leishmania donovani exploits h ...... subvert host immune response.
@nl
type
label
Leishmania donovani exploits h ...... subvert host immune response.
@en
Leishmania donovani exploits h ...... subvert host immune response.
@nl
prefLabel
Leishmania donovani exploits h ...... subvert host immune response.
@en
Leishmania donovani exploits h ...... subvert host immune response.
@nl
P2093
P356
P1476
Leishmania donovani exploits h ...... subvert host immune response.
@en
P2093
Pijush K Das
Robin Mukhopadhyaya
Supriya Srivastav
Susanta Kar
P304
P356
10.4049/JIMMUNOL.1102845
P407
P577
2012-06-08T00:00:00Z