Cloning, characterization, and expression in Escherichia coli of the Streptomyces clavuligerus gene encoding deacetoxycephalosporin C synthetase.

Cloning, characterization, and expression in Escherichia coli of the Streptomyces clavuligerus gene encoding deacetoxycephalosporin C synthetase.

Item
http://www.wikidata.org/entity/Q39947876
Molecular regulation of beta-lactam biosynthesis in filamentous fungiMolecular characterization of the acyl-coenzyme A:isopenicillin N acyltransferase gene (penDE) from Penicillium chrysogenum and Aspergillus nidulans and activity of recombinant enzyme in Escherichia coliIsolation and characterization of a beta-lactamase-inhibitory protein from Streptomyces clavuligerus and cloning and analysis of the corresponding geneCloning and location of a gene governing lysine epsilon-aminotransferase, an enzyme initiating beta-lactam biosynthesis in Streptomyces spp.Beta-lactam antibiotic biosynthetic genes have been conserved in clusters in prokaryotes and eukaryotes.Directed evolution of Streptomyces clavuligerus deacetoxycephalosporin C synthase for enhancement of penicillin G expansion.Engineering Streptomyces clavuligerus deacetoxycephalosporin C synthase for optimal ring expansion activity toward penicillin GReconstitution of TCA cycle with DAOCS to engineer Escherichia coli into an efficient whole cell catalyst of penicillin G.Family shuffling of expandase genes to enhance substrate specificity for penicillin G.Molecular biology of penicillin and cephalosporin biosynthesis.The beta-lactam biosynthesis genes for isopenicillin N epimerase and deacetoxycephalosporin C synthetase are expressed from a single transcript in Streptomyces clavuligerus.A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: amplification results in overproduction of both beta-lactam compounds.Cloning and sequencing of the beta-lactam hydroxylase gene (cefF) from Streptomyces clavuligerus: gene duplication may have led to separate hydroxylase and expandase activities in the actinomycetes.Localization of the lysine epsilon-aminotransferase (lat) and delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase (pcbAB) genes from Streptomyces clavuligerus and production of lysine epsilon-aminotransferase activity in Escherichia coli.Involvement of Fe uptake systems and AmpC β-lactamase in susceptibility to the siderophore monosulfactam BAL30072 in Pseudomonas aeruginosa.Modification of vertebrate and algal prolyl 4-hydroxylases and vertebrate lysyl hydroxylase by diethyl pyrocarbonate. Evidence for histidine residues in the catalytic site of 2-oxoglutarate-coupled dioxygenases.Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in β-lactam biosynthesis
P2860

Cloning, characterization, and expression in Escherichia coli of the Streptomyces clavuligerus gene encoding deacetoxycephalosporin C synthetase.

Item
http://www.wikidata.org/entity/Q39947876
description
1989 nî lūn-bûn
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1989年の論文
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1989年学术文章
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1989年学术文章
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1989年学术文章
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@zh-my
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1989年學術文章
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1989年學術文章
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name
Cloning, characterization, and ...... oxycephalosporin C synthetase.
@en
Cloning, characterization, and ...... oxycephalosporin C synthetase.
@nl
type
label
Cloning, characterization, and ...... oxycephalosporin C synthetase.
@en
Cloning, characterization, and ...... oxycephalosporin C synthetase.
@nl
prefLabel
Cloning, characterization, and ...... oxycephalosporin C synthetase.
@en
Cloning, characterization, and ...... oxycephalosporin C synthetase.
@nl
P1433
P1476
P2093
P2860
P304
P31
P433
P478
P577
P698
P921
P932
P1433
P1476
Cloning, characterization, and ...... oxycephalosporin C synthetase.
@en
P2093
P2860
P304
P31
P433
P478
P577
P698
P921
P932