Investigation of transport mechanisms and regulation of intracellular Zn2+ in pancreatic alpha-cells. - Wikidata - awgldk - TriplyDB

Investigation of transport mechanisms and regulation of intracellular Zn2+ in pancreatic alpha-cells.

Investigation of transport mechanisms and regulation of intracellular Zn2+ in pancreatic alpha-cells.

http://www.wikidata.org/entity/Q40016539

about

Zinc and diabetes mellitus: understanding molecular mechanisms and clinical implications Zinc transporter 8 (ZnT8) and β cell function The physiological effects of deleting the mouse SLC30A8 gene encoding zinc transporter-8 are influenced by gender and genetic background Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants Zinc and zinc transporter regulation in pancreatic islets and the potential role of zinc in islet transplantation Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion ATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation.Exploring the Association Between Demographics, SLC30A8 Genotype, and Human Islet Content of Zinc, Cadmium, Copper, Iron, Manganese and Nickel Zinc transporter ZIP14 functions in hepatic zinc, iron and glucose homeostasis during the innate immune response (endotoxemia).Zinc in specialized secretory tissues: roles in the pancreas, prostate, and mammary gland.Zip4 mediated zinc influx stimulates insulin secretion in pancreatic beta cells.Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion MafA and MafB regulate genes critical to beta-cells in a unique temporal manner Physiologic implications of metal-ion transport by ZIP14 and ZIP8 UCP2 regulates the glucagon response to fasting and starvation Imaging the Beta-cell mass: why and how SLC30A8 (ZnT8) Polymorphism is Associated with Young Age at Type 1 Diabetes Onset.Mouse pancreatic endocrine cell transcriptome defined in the embryonic Ngn3-null mouse.UCP2 is highly expressed in pancreatic alpha-cells and influences secretion and survival.Insulin as a physiological modulator of glucagon secretion.Analysis of Zinc-Exporters Expression in Prostate Cancer.ZnT8 autoantibody titers in type 1 diabetes patients decline rapidly after clinical onset Regulation of glucagon secretion by zinc: lessons from the β cell-specific Znt8 knockout mouse model.ZnT3: a zinc transporter active in several organs.Contribution of calcium-conducting channels to the transport of zinc ions.Zinc and insulin in pancreatic beta-cells.The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism.Characterization of the human SLC30A8 promoter and intronic enhancer The plasma membrane metal-ion transporter ZIP14 contributes to nontransferrin-bound iron uptake by human β-cells.Unperturbed islet α-cell function examined in mouse pancreas tissue slices.Expression of the ZIP/SLC39A transporters in β-cells: a systematic review and integration of multiple datasets.The pancreatic islet β-cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer.Characterization of Erg K+ channels in alpha- and beta-cells of mouse and human islets.Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells.Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.Transcriptional analysis of intracytoplasmically stained, FACS-purified cells by high-throughput, quantitative nuclease protection.Zinc supplementation in prediabetes: A randomized double-blind placebo-controlled clinical trial.Implications of impaired zinc homeostasis in diabetic cardiomyopathy and nephropathy.A subclass of serum anti-ZnT8 antibodies directed to the surface of live pancreatic β-cells.Intracellular zinc in insulin secretion and action: a determinant of diabetes risk?

P2860

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P2860

Investigation of transport mechanisms and regulation of intracellular Zn2+ in pancreatic alpha-cells.

http://www.wikidata.org/entity/Q40016539

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

Investigation of transport mec ...... n2+ in pancreatic alpha-cells.

@en

type

label

Investigation of transport mec ...... n2+ in pancreatic alpha-cells.

@en

prefLabel

Investigation of transport mec ...... n2+ in pancreatic alpha-cells.

@en

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P1433

Journal of Biological Chemistry

P1476

Investigation of transport mec ...... Zn2+ in pancreatic alpha-cells

@en

P2093

Alpana Bhattacharjee

http://www.w3.org/2001/XMLSchema#string

Armen V Gyulkhandanyan

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Feihan F Dai

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Hongfang Lu

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Jocelyn E Manning Fox

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Nadeeja Wijesekara

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Simon C Lee

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P2860

The human ZIP1 transporter mediates zinc uptake in human K562 erythroleukemia cells

Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

The unique cytoarchitecture of human pancreatic islets has implications for islet cell function

Zinc and the Msc2 zinc transporter protein are required for endoplasmic reticulum function.

Efflux and compartmentalization of zinc by members of the SLC30 family of solute carriers

The SLC39 family of metal ion transporters

Structure, function, and regulation of a subfamily of mouse zinc transporter genes

ZnT7, a novel mammalian zinc transporter, accumulates zinc in the Golgi apparatus

P304

10184-10197

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scholarly article

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10.1074/JBC.M707005200

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P433

15

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P478

283

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P50

Michael B. Wheeler

Fabrice Chimienti

P577

2008-02-04T00:00:00Z

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P698

18250168

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