Investigation of transport mechanisms and regulation of intracellular Zn2+ in pancreatic alpha-cells.
about
Zinc and diabetes mellitus: understanding molecular mechanisms and clinical implicationsZinc transporter 8 (ZnT8) and β cell functionThe physiological effects of deleting the mouse SLC30A8 gene encoding zinc transporter-8 are influenced by gender and genetic backgroundInsulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variantsZinc and zinc transporter regulation in pancreatic islets and the potential role of zinc in islet transplantationDeletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretionATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation.Exploring the Association Between Demographics, SLC30A8 Genotype, and Human Islet Content of Zinc, Cadmium, Copper, Iron, Manganese and NickelZinc transporter ZIP14 functions in hepatic zinc, iron and glucose homeostasis during the innate immune response (endotoxemia).Zinc in specialized secretory tissues: roles in the pancreas, prostate, and mammary gland.Zip4 mediated zinc influx stimulates insulin secretion in pancreatic beta cells.Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretionMafA and MafB regulate genes critical to beta-cells in a unique temporal mannerPhysiologic implications of metal-ion transport by ZIP14 and ZIP8UCP2 regulates the glucagon response to fasting and starvationImaging the Beta-cell mass: why and howSLC30A8 (ZnT8) Polymorphism is Associated with Young Age at Type 1 Diabetes Onset.Mouse pancreatic endocrine cell transcriptome defined in the embryonic Ngn3-null mouse.UCP2 is highly expressed in pancreatic alpha-cells and influences secretion and survival.Insulin as a physiological modulator of glucagon secretion.Analysis of Zinc-Exporters Expression in Prostate Cancer.ZnT8 autoantibody titers in type 1 diabetes patients decline rapidly after clinical onsetRegulation of glucagon secretion by zinc: lessons from the β cell-specific Znt8 knockout mouse model.ZnT3: a zinc transporter active in several organs.Contribution of calcium-conducting channels to the transport of zinc ions.Zinc and insulin in pancreatic beta-cells.The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism.Characterization of the human SLC30A8 promoter and intronic enhancerThe plasma membrane metal-ion transporter ZIP14 contributes to nontransferrin-bound iron uptake by human β-cells.Unperturbed islet α-cell function examined in mouse pancreas tissue slices.Expression of the ZIP/SLC39A transporters in β-cells: a systematic review and integration of multiple datasets.The pancreatic islet β-cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer.Characterization of Erg K+ channels in alpha- and beta-cells of mouse and human islets.Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells.Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.Transcriptional analysis of intracytoplasmically stained, FACS-purified cells by high-throughput, quantitative nuclease protection.Zinc supplementation in prediabetes: A randomized double-blind placebo-controlled clinical trial.Implications of impaired zinc homeostasis in diabetic cardiomyopathy and nephropathy.A subclass of serum anti-ZnT8 antibodies directed to the surface of live pancreatic β-cells.Intracellular zinc in insulin secretion and action: a determinant of diabetes risk?
P2860
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P2860
Investigation of transport mechanisms and regulation of intracellular Zn2+ in pancreatic alpha-cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Investigation of transport mec ...... n2+ in pancreatic alpha-cells.
@en
type
label
Investigation of transport mec ...... n2+ in pancreatic alpha-cells.
@en
prefLabel
Investigation of transport mec ...... n2+ in pancreatic alpha-cells.
@en
P2093
P2860
P50
P356
P1476
Investigation of transport mec ...... Zn2+ in pancreatic alpha-cells
@en
P2093
Alpana Bhattacharjee
Armen V Gyulkhandanyan
Feihan F Dai
Hongfang Lu
Jocelyn E Manning Fox
Nadeeja Wijesekara
Simon C Lee
P2860
P304
10184-10197
P356
10.1074/JBC.M707005200
P407
P577
2008-02-04T00:00:00Z