Phenotypic differences in PFIC2 and BRIC2 correlate with protein stability of mutant Bsep and impaired taurocholate secretion in MDCK II cells. - Wikidata - awgldk - TriplyDB

Phenotypic differences in PFIC2 and BRIC2 correlate with protein stability of mutant Bsep and impaired taurocholate secretion in MDCK II cells.

Phenotypic differences in PFIC2 and BRIC2 correlate with protein stability of mutant Bsep and impaired taurocholate secretion in MDCK II cells.

http://www.wikidata.org/entity/Q40065684

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Progressive familial intrahepatic cholestasis Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): functional characterization and interindividual variability Bile acid transporters in health and disease Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicing Genetics and Molecular Modeling of New Mutations of Familial Intrahepatic Cholestasis in a Single Italian Center Clinical application of transcriptional activators of bile salt transporters.Bile formation and secretion.The bile salt export pump: clinical and experimental aspects of genetic and acquired cholestatic liver disease An updated review on drug-induced cholestasis: mechanisms and investigation of physicochemical properties and pharmacokinetic parameters.Scoparone potentiates transactivation of the bile salt export pump gene and this effect is enhanced by cytochrome P450 metabolism but abolished by a PKC inhibitor.A C-terminal tyrosine-based motif in the bile salt export pump directs clathrin-dependent endocytosis.Abcb11 deficiency induces cholestasis coupled to impaired β-fatty acid oxidation in mice Biosynthesis and trafficking of the bile salt export pump, BSEP: therapeutic implications of BSEP mutations.Muscarinic 2 receptors modulate cardiac proteasome function in a protein kinase G-dependent manner.Recent advances in the exploration of the bile salt export pump (BSEP/ABCB11) function.Successful treatment with 4-phenylbutyrate in a patient with benign recurrent intrahepatic cholestasis type 2 refractory to biliary drainage and bilirubin absorption.Degradation of the bile salt export pump at endoplasmic reticulum in progressive familial intrahepatic cholestasis type II Ursodeoxycholic acid stabilizes the bile salt export pump in the apical membrane in MDCK II cells.Targeted pharmacotherapy in progressive familial intrahepatic cholestasis type 2: Evidence for improvement of cholestasis with 4-phenylbutyrate.Outcomes of surgical management of familial intrahepatic cholestasis 1 and bile salt export protein deficiencies.Jaundice revisited: recent advances in the diagnosis and treatment of inherited cholestatic liver diseases

P2860

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P2860

Phenotypic differences in PFIC2 and BRIC2 correlate with protein stability of mutant Bsep and impaired taurocholate secretion in MDCK II cells.

http://www.wikidata.org/entity/Q40065684

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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name

Phenotypic differences in PFIC ...... te secretion in MDCK II cells.

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type

label

Phenotypic differences in PFIC ...... te secretion in MDCK II cells.

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Phenotypic differences in PFIC ...... te secretion in MDCK II cells.

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American Journal of Physiology - Gastrointestinal and Liver Physiology

P1476

Phenotypic differences in PFIC ...... te secretion in MDCK II cells.

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Asano Numari

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Hirotoshi Tanaka

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Irwin M Arias

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Johbu Itoh

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Kaori Mochizuki

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Norihito Watanabe

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Tatehiro Kagawa

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Tetsuya Mine

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Yoshie Ikeno

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P2860

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis

BSEP: function and role in progressive familial intrahepatic cholestasis

GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Progressive familial intrahepatic cholestasis: genetic disorders of biliary transporters

Impaired expression and function of the bile salt export pump due to three novel ABCB11 mutations in intrahepatic cholestasis

ERAD: the long road to destruction

Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11

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17947449

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