Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TC.
about
Human inter-individual variability in metabolism and genotoxic response to zidovudineCentrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cellsExposure of Allium cepa root cells to zidovudine or nevirapine induces cytogenotoxic changesFoetal loss and enhanced fertility observed in mice treated with Zidovudine or NevirapineGenotoxic and Cytotoxic Effects of Antiretroviral Combinations in Mice Bone MarrowInhibition of NF-κB activation sensitizes U937 cells to 3'-azido-3'-deoxythymidine induced apoptosisMutational analysis of the mitochondrial tRNA genes and flanking regions in umbilical cord tissue from uninfected infants receiving AZT-based therapies for prophylaxis of HIV-1.WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication.Comparing genotoxic signatures in cord blood cells from neonates exposed in utero to zidovudine or tenofovir.Perinatal exposure of patas monkeys to antiretroviral nucleoside reverse-transcriptase inhibitors induces genotoxicity persistent for up to 3 years of ageLong-term exposure to zidovudine delays cell cycle progression, induces apoptosis, and decreases telomerase activity in human hepatocytes.Effects of in utero antiretroviral exposure on mitochondrial DNA levels, mitochondrial function and oxidative stress.Tolerance of the newborn to antiretroviral drug exposure in utero.Differential gene expression in human hepatocyte cell lines exposed to the antiretroviral agent zidovudine.Molecular analysis of mitochondrial compromise in rodent cardiomyocytes exposed long term to nucleoside reverse transcriptase inhibitors (NRTIs).Defunct gadgets and changing times.Assessment of genotoxicity induced by 7,12-dimethylbenz(a)anthracene or diethylnitrosamine in the Pig-a, micronucleus and Comet assays integrated into 28-day repeat dose studies.Next generation high throughput DNA damage detection platform for genotoxic compound screening.
P2860
Q23918962-6A18CB7A-D465-4D60-AAD1-B112244AD2F7Q28388689-486B20E4-0722-400E-B0D7-538F7B385803Q28540477-C8C76F4A-6D88-4C75-9150-8FE0121160BDQ28543074-4FB2AA5B-CE93-4C58-9DC5-F71CC5DE2E94Q28553106-173A9DD7-BEBD-44E0-AC1F-FAEFE674752FQ34561763-1105E438-C9CA-415C-8C3B-6EA06B0EF869Q35327135-D66ADE78-E583-40A4-8AA3-4231C9413153Q35394336-8EBA8486-B25C-444C-94A1-AB887BA9E175Q35853818-060E84F4-22A5-42F3-B762-F6292F8697A6Q36936334-9C0FF57E-3DC5-472E-80D5-B624769A867DQ37324745-BA5E236F-9960-4C6C-919F-B28CF6139541Q37552456-14D263E4-5F2F-40DE-BFA9-5E9AA2867E0FQ38366365-921D5DEF-19DD-4FEB-8018-4B14E47A63B4Q39051706-7E89D9F4-3CCB-40B5-B418-EC4988E2517DQ39428374-7FEFAA11-162B-450E-AC2C-09EE45B60C0BQ46099461-27B00FA5-AF88-4576-98EC-A25492118C29Q46747455-BC6AF03B-39E0-4AB7-AB99-7567EF362E56Q49394134-67214768-9CBE-4EA5-BE69-CF69F012BC3F
P2860
Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TC.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Genotoxicity assessed by the c ...... child pairs to AZT or AZT-3TC.
@en
type
label
Genotoxicity assessed by the c ...... child pairs to AZT or AZT-3TC.
@en
prefLabel
Genotoxicity assessed by the c ...... child pairs to AZT or AZT-3TC.
@en
P2093
P2860
P356
P1476
Genotoxicity assessed by the c ...... child pairs to AZT or AZT-3TC.
@en
P2093
Billy W Day
Carol J Nesel
Dale M Walker
J Patrick O'Neill
Miriam C Poirier
Nancy A Wade
Ofelia A Olivero
Patricia A Escobar
Quanxin Meng
Richard D Day
P2860
P304
P356
10.1002/EM.20285
P577
2007-04-01T00:00:00Z