Structure-function analysis of Arg-Gly-Asp helix motifs in alpha v beta 6 integrin ligands.
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P1343
Molecular imaging of integrin αvβ6 expression in living subjects.The role of integrins in TGFβ activation in the tumour stromaMolecular basis of the recognition of nephronectin by integrin alpha8beta1NMR relaxation and structural elucidation of peptides in the presence and absence of trifluoroethanol illuminates the critical molecular nature of integrin αvβ6 ligand specificity.Synthesis and characterization of a high-affinity {alpha}v{beta}6-specific ligand for in vitro and in vivo applications.Dimerization of a phage-display selected peptide for imaging of αvβ6- integrin: two approaches to the multivalent effect.Evaluation of [64Cu]Cu-DOTA and [64Cu]Cu-CB-TE2A chelates for targeted positron emission tomography with an alphavbeta6-specific peptideWhy integrin as a primary target for imaging and therapy.Integrin targeted delivery of radiotherapeutics.Structural guided scaffold phage display libraries as a source of bio-therapeutics.Generation and characterization of a diabody targeting the αvβ6 integrin.In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery.In vitro potency, in vitro and in vivo efficacy of liposomal alendronate in combination with γδ T cell immunotherapy in mice.Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells.Tumor Targeting via Integrin Ligands.Three-dimensional structure of foot-and-mouth disease virus and its biological functions.Post-coupling strategy enables true receptor-targeted nanoparticles.Suppression of Hedgehog signalling promotes pro-tumourigenic integrin expression and function.A human monoclonal antibody 264RAD targeting αvβ6 integrin reduces tumour growth and metastasis, and modulates key biomarkers in vivo.In vivo positron emission tomography (PET) imaging with an alphavbeta6 specific peptide radiolabeled using 18F-"click" chemistry: evaluation and comparison with the corresponding 4-[18F]fluorobenzoyl- and 2-[18F]fluoropropionyl-peptides.Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus.Guinea pig-adapted foot-and-mouth disease virus with altered receptor recognition can productively infect a natural host.Q2DSTD NMR deciphers epitope-mapping variability for peptide recognition of integrin αvβ6.Investigating in vitro and in vivo αvβ6 integrin receptor-targeting liposomal alendronate for combinatory γδ T cell immunotherapy.A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins.Optimising selective excitation pulses to maximise saturation transfer difference NMR spectroscopy.Molecular Basis of the Ligand Binding Specificity of αvβ8 Integrin.Foot-and-mouth disease virus forms a highly stable, EDTA-resistant complex with its principal receptor, integrin alphavbeta6: implications for infectiousnessPositively charged residues at the five-fold symmetry axis of cell culture-adapted foot-and-mouth disease virus permit novel receptor interactions.Investigating the Interaction of Cyclic RGD Peptidomimetics with αVβ₆ Integrin by Biochemical and Molecular Docking Studies.Chromogranin A binds to αvβ6-integrin and promotes wound healing in mice.Designer Oncolytic Adenovirus: Coming of Age.
P2860
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P2860
Structure-function analysis of Arg-Gly-Asp helix motifs in alpha v beta 6 integrin ligands.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Structure-function analysis of ...... pha v beta 6 integrin ligands.
@en
type
label
Structure-function analysis of ...... pha v beta 6 integrin ligands.
@en
prefLabel
Structure-function analysis of ...... pha v beta 6 integrin ligands.
@en
P2093
P2860
P356
P1476
Structure-function analysis of ...... pha v beta 6 integrin ligands.
@en
P2093
Chiara Rapisarda
Danielle DiCara
Ian R Hart
John F Marshall
Julie L Sutcliffe
Mark J Howard
Paul H Weinreb
Shelia M Violette
P2860
P304
P356
10.1074/JBC.M610461200
P407
P4510
P577
2007-01-23T00:00:00Z