Anthrax toxin protective antigen: inhibition of channel function by chloroquine and related compounds and study of binding kinetics using the current noise analysis.
about
Obstructing toxin pathways by targeted pore blockageTailored ß-cyclodextrin blocks the translocation pores of binary exotoxins from C. botulinum and C. perfringens and protects cells from intoxicationRole of N-terminal His6-Tags in binding and efficient translocation of polypeptides into cells using anthrax protective antigen (PA)Use of nonelectrolytes reveals the channel size and oligomeric constitution of the Borrelia burgdorferi P66 porinEffects of spontaneous deamidation on the cytotoxic activity of the Bacillus anthracis protective antigen.Blockage of anthrax PA63 pore by a multicharged high-affinity toxin inhibitor.Cross-reactivity of anthrax and C2 toxin: protective antigen promotes the uptake of botulinum C2I toxin into human endothelial cellsBlocking anthrax lethal toxin at the protective antigen channel by using structure-inspired drug design.Channel-forming bacterial toxins in biosensing and macromolecule deliveryDesigned azolopyridinium salts block protective antigen pores in vitro and protect cells from anthrax toxin.Designing inhibitors of anthrax toxinInteractions of high-affinity cationic blockers with the translocation pores of B. anthracis, C. botulinum, and C. perfringens binary toxins.Sizing the Bacillus anthracis PA63 channel with nonelectrolyte poly(ethylene glycols)Inhibiting bacterial toxins by channel blockage.Anthrax toxin-induced rupture of artificial lipid bilayer membranes.Impact of Dendrimer Terminal Group Chemistry on Blockage of the Anthrax Toxin Channel: A Single Molecule Study.Membrane translocation by anthrax toxin.An overview of investigational toxin-directed therapies for the adjunctive management of Bacillus anthracis infection and sepsis.Protection against Shiga ToxinsChloroquine Analog Interaction with C2- and Iota-Toxin in Vitro and in Living Cells.Cationic PAMAM dendrimers as pore-blocking binary toxin inhibitors.Toxin Transport by A-B Type of Toxins in Eukaryotic Target Cells and Its Inhibition by Positively Charged Heterocyclic Molecules.Chloroquine derivatives block the translocation pores and inhibit cellular entry of Clostridium botulinum C2 toxin and Bacillus anthracis lethal toxin.Residues involved in the pore-forming activity of the Clostridium perfringens iota toxin.Clostridium botulinum C2 toxin. Identification of the binding site for chloroquine and related compounds and influence of the binding site on properties of the C2II channel.TcdA1 of Photorhabdus luminescens: electrophysiological analysis of pore formation and effector binding.Hofmeister effect in confined spaces: halogen ions and single molecule detection.A phenylalanine clamp catalyzes protein translocation through the anthrax toxin pore.Effect of endosomal acidification on small ion transport through the anthrax toxin PA63 channel.Anthrax Edema Factor, Voltage-dependent Binding to the Protective Antigen Ion Channel and Comparison to LF BindingEnterotoxin: The Toxin Forms Highly Cation-Selective Channels in Lipid Bilayers
P2860
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P2860
Anthrax toxin protective antigen: inhibition of channel function by chloroquine and related compounds and study of binding kinetics using the current noise analysis.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Anthrax toxin protective antig ...... ng the current noise analysis.
@en
type
label
Anthrax toxin protective antig ...... ng the current noise analysis.
@en
prefLabel
Anthrax toxin protective antig ...... ng the current noise analysis.
@en
P2860
P1433
P1476
Anthrax toxin protective antig ...... ng the current noise analysis.
@en
P2093
Bettina Schiffler
Frank Orlik
P2860
P304
P356
10.1529/BIOPHYSJ.104.050336
P407
P50
P577
2004-12-13T00:00:00Z