The cleavage of microphthalmia-associated transcription factor, MITF, by caspases plays an essential role in melanocyte and melanoma cell apoptosis
about
Mitf regulation of Dia1 controls melanoma proliferation and invasivenessFifteen-year quest for microphthalmia-associated transcription factor target genesMicrophthalmia-associated transcription factor regulates RAB27A gene expression and controls melanosome transportThe capsid proteins of Aleutian mink disease virus activate caspases and are specifically cleaved during infectionA myosin-Va tail fragment sequesters dynein light chains leading to apoptosis in melanoma cells.Networks and pathways in pigmentation, health, and disease.SIRT1 promotes proliferation and inhibits the senescence-like phenotype in human melanoma cells.Coordinated regulation of chromatophore differentiation and melanogenesis during the ontogeny of skin pigmentation of Solea senegalensis (Kaup, 1858).Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)Ciglitazone negatively regulates CXCL1 signaling through MITF to suppress melanoma growth.MITF in melanoma: mechanisms behind its expression and activity.A role for tyrosinase-related protein 1 in 4-tert-butylphenol-induced toxicity in melanocytes: Implications for vitiligo.SOX9 is a key player in ultraviolet B-induced melanocyte differentiation and pigmentationGenetic evidence for critical roles of P38α protein in regulating mast cell differentiation and chemotaxis through distinct mechanisms.Aurora B is regulated by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and is a valuable potential target in melanoma cells.Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-M(high) melanoma cell populationsRecent discoveries in the genetics of melanoma and their therapeutic implications.Secretome from senescent melanoma engages the STAT3 pathway to favor reprogramming of naive melanoma towards a tumor-initiating cell phenotype.Light-regulated microRNAs.Constitutive ERK activity induces downregulation of tristetraprolin, a major protein controlling interleukin8/CXCL8 mRNA stability in melanoma cells.Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny.Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma.Therapeutic RNA interference of malignant melanoma by electrotransfer of small interfering RNA targeting Mitf.The MAPK pathway functions as a redundant survival signal that reinforces the PI3K cascade in c-Kit mutant melanoma.The microphthalmia-associated transcription factor requires SWI/SNF enzymes to activate melanocyte-specific genes.Evolutionary sequence comparison of the Mitf gene reveals novel conserved domains.A direct link between MITF, innate immunity, and hair graying.
P2860
Q24672631-59056039-E219-4F9A-A54F-4C64F45874C0Q28267024-0D3BBEF1-995D-4B98-A78C-B1EE3807169EQ28269029-28708935-26D2-448E-A96E-92BD8A7F2464Q28269070-DED45F11-C4F4-4E8B-9F98-D609B9EF3CDAQ30538270-B8E15FB4-AE1C-4687-ACAB-B05D4310BCA0Q33584524-C8A755B8-DC8C-4933-9331-4A779B58A799Q33688529-C4241615-3C7C-4C58-8E8D-BED6C954A816Q34720934-D303A4B7-9AF2-42BE-8336-9FB874E7145DQ35080064-0D7F3331-233B-4B90-8D96-60999F56E07FQ35092571-69A3C91F-75D9-4A0C-9F15-2382B8A1011FQ35187734-8703EC9B-EDAB-498F-8233-167A85DA7305Q35607292-F627C594-ADC2-4CAF-A985-29F866EBFD43Q35956740-1D77770F-D367-488C-8C7E-1E01807DAAE4Q36016892-D008235C-F950-4C7B-901B-C692EAEB5A6EQ36215925-47BA507F-D872-4021-8C8C-3DBF2DEF2896Q36962495-F2E07BCB-7125-453B-9A42-B1AAB29C746FQ37024839-C086F215-A13E-476C-B8B8-717B9489B706Q37589120-F1A2732E-D226-4B73-B8CF-0E116ECECF27Q38267349-682C2192-23F6-4D3D-AE23-A385FC680ED9Q39540154-5FCDC282-B4E3-40E4-8C9E-8663E4BC34D4Q39600607-80FE43B2-7A6F-4802-9346-2736657A66A1Q39604101-ED7EF41E-29AB-44C6-87E1-EAF149505DDAQ40223081-53BE6E89-D78E-4AA6-A256-F9359BBD60CAQ44073293-ADB76052-79AA-46FF-B948-691C112F38E0Q52019222-9148DA70-8A9C-4CE2-A0AD-AB3C0F0814AFQ52679967-D6E570D3-9F79-4289-A3CC-1C380EE8700DQ54959863-5AEA18F6-59D9-4649-873A-C6C07792A3D4
P2860
The cleavage of microphthalmia-associated transcription factor, MITF, by caspases plays an essential role in melanocyte and melanoma cell apoptosis
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
The cleavage of microphthalmia ...... te and melanoma cell apoptosis
@en
type
label
The cleavage of microphthalmia ...... te and melanoma cell apoptosis
@en
prefLabel
The cleavage of microphthalmia ...... te and melanoma cell apoptosis
@en
P2093
P2860
P50
P356
P1433
P1476
The cleavage of microphthalmia ...... te and melanoma cell apoptosis
@en
P2093
Caroline Hilmi
Jean Paul Ortonne
Karine Bille
Lionel Larribere
Mehdi Khaled
P2860
P304
P356
10.1101/GAD.335905
P577
2005-09-01T00:00:00Z