The copper influx transporter human copper transport protein 1 regulates the uptake of cisplatin in human ovarian carcinoma cells.
about
Projection structure of the human copper transporter CTR1 at 6-A resolution reveals a compact trimer with a novel channel-like architecture.Role of copper transporters in platinum resistanceMechanism of Platinum Derivatives Induced Kidney InjuryMechanisms of Cisplatin nephrotoxicityThe path for metal complexes to a DNA targetDifferential expression of ATP7A, ATP7B and CTR1 in adult rat dorsal root ganglion tissueMembrane transporters as mediators of Cisplatin effects and side effects.The role of metal binding and phosphorylation domains in the regulation of cisplatin-induced trafficking of ATP7B.Targeted quantitative analysis of superoxide dismutase 1 in cisplatin-sensitive and cisplatin-resistant human ovarian cancer cells.Protein kinase inhibitors emodin and dichloro-ribofuranosylbenzimidazole modulate the cellular accumulation and cytotoxicity of cisplatin in a schedule-dependent manner.Regulation of copper transporter 2 expression by copper and cisplatin in human ovarian carcinoma cells.Uptake of compounds that selectively kill multidrug-resistant cells: the copper transporter SLC31A1 (CTR1) increases cellular accumulation of the thiosemicarbazone NSC73306The role of the methionines and histidines in the transmembrane domain of mammalian copper transporter 1 in the cellular accumulation of cisplatinRegulation of Cisplatin cytotoxicity by cu influx transporters.DNA-bound platinum is the major determinant of cisplatin sensitivity in head and neck squamous carcinoma cells.OTOTOXIC EFFECTS OF CARBOPLATIN IN ORGANOTYPIC CULTURES IN CHINCHILLAS AND RATSMolecular modulation of the copper and cisplatin transport function of CTR1 and its interaction with IRS-4.Gender difference in Cisplatin-induced nephrotoxicity in a rat model.Copper transporters and the cellular pharmacology of the platinum-containing cancer drugs.EGCG Enhances Cisplatin Sensitivity by Regulating Expression of the Copper and Cisplatin Influx Transporter CTR1 in Ovary CancerMolecular mechanisms of resistance and toxicity associated with platinating agents.Different gap junction-propagated effects on cisplatin transfer result in opposite responses to cisplatin in normal cells versus tumor cells.Platinum (IV)-fatty acid conjugates overcome inherently and acquired Cisplatin resistant cancer cell lines: an in-vitro study.The CXXC motifs in the metal binding domains are required for ATP7B to mediate resistance to cisplatin.Molecular markers of chemotherapeutic response and toxicity in colorectal cancer.ATP11B mediates platinum resistance in ovarian cancer.A re-evaluation of the role of hCTR1, the human high-affinity copper transporter, in platinum-drug entry into human cellsIncreasing cGMP-dependent protein kinase I activity attenuates cisplatin-induced kidney injury through protection of mitochondria functionTranscriptome analysis of copper homeostasis genes reveals coordinated upregulation of SLC31A1,SCO1, and COX11 in colorectal cancer.The role of the mammalian copper transporter 1 in the cellular accumulation of platinum-based drugsLabel-free mass spectrometry-based protein quantification technologies in proteomic analysis.Enhanced delivery of cisplatin to intraperitoneal ovarian carcinomas mediated by the effects of bortezomib on the human copper transporter 1Role of copper transporters in resistance to platinating agents.Inhibition of transcription by platinum antitumor compoundsOrganic cation transporters are determinants of oxaliplatin cytotoxicity.Interaction of classical platinum agents with the monomeric and dimeric Atox1 proteins: a molecular dynamics simulation study.Roles of Atox1 and p53 in the trafficking of copper-64 to tumor cell nuclei: implications for cancer therapyCharacterization of a monoclonal antibody capable of reliably quantifying expression of human Copper Transporter 1 (hCTR1)Mechanism of tumor resistance to cisplatin mediated by the copper transporter ATP7B.Advances in the understanding of mammalian copper transporters.
P2860
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P2860
The copper influx transporter human copper transport protein 1 regulates the uptake of cisplatin in human ovarian carcinoma cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The copper influx transporter ...... human ovarian carcinoma cells.
@en
type
label
The copper influx transporter ...... human ovarian carcinoma cells.
@en
prefLabel
The copper influx transporter ...... human ovarian carcinoma cells.
@en
P2093
P356
P1476
The copper influx transporter ...... human ovarian carcinoma cells.
@en
P2093
Alison K Holzer
Goli Samimi
Kuniyuki Katano
Roohangiz Safaei
Stephen B Howell
Wiltrud Naerdemann
Xinjian Lin
P304
P356
10.1124/MOL.104.001198
P577
2004-06-30T00:00:00Z