about
Disease-specific induced pluripotent stem cellsOct4 expression is not required for mouse somatic stem cell self-renewalDirect in vivo VH to JH rearrangement violating the 12/23 rule.Chromatin dynamics during cellular reprogrammingNuclear reprogramming and pluripotencyImmortalization eliminates a roadblock during cellular reprogramming into iPS cellsThe THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogrammingThe polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early developmentEfficient generation of iPS cells from skeletal muscle stem cellsLgr5-positive supporting cells generate new hair cells in the postnatal cochlea.Phf8 loss confers resistance to depression-like and anxiety-like behaviors in miceDistinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation.Reprogramming of pancreatic beta cells into induced pluripotent stem cellsTCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexesTgfbeta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMycAberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells.A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs.The histone chaperone CAF-1 safeguards somatic cell identity.Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes.Harnessing the potential of induced pluripotent stem cells for regenerative medicine.Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei.Induced pluripotency: history, mechanisms, and applications.Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice.Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cellsT-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell.ES cells derived from cloned and fertilized blastocysts are transcriptionally and functionally indistinguishable.Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues.Nuclear cloning, epigenetic reprogramming and cellular differentiation.Nucleosomal occupancy changes locally over key regulatory regions during cell differentiation and reprogramming.A high-efficiency system for the generation and study of human induced pluripotent stem cells.Guidelines and techniques for the generation of induced pluripotent stem cells.Nuclear transplantation: lessons from frogs and mice.Small molecules facilitate rapid and synchronous iPSC generation.Nuclear cloning, stem cells, and genomic reprogramming.Nuclear transplantation, embryonic stem cells, and the potential for cell therapy.Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastomaNuclear transplantation, embryonic stem cells and the potential for cell therapy.Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization.Mediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency.X chromosome choice occurs independently of asynchronous replication timing.
P50
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P50
description
ahli biologi
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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Konrad Hochedlinger
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