Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.
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Analysis of the p63 gene in classical EEC syndrome, related syndromes, and non-syndromic orofacial cleftsIARC Database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation toolsFactors governing loss and rescue of DNA binding upon single and double mutations in the p53 core domain.Reduction of gene repair by selenomethionine with the use of single-stranded oligonucleotides.Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrestRegulation of MCP-1 chemokine transcription by p53Genetic mutation analysis of human gastric adenocarcinomas using ion torrent sequencing platform.Effects of temperature on the p53-DNA binding interactions and their dynamical behavior: comparing the wild type to the R248Q mutant.TP53 mutations in nonsmall cell lung cancerp53 gene mutation: software and database.APC gene: database of germline and somatic mutations in human tumors and cell lines.Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects.A specific spectrum of p53 mutations in lung cancer from smokers: review of mutations compiled in the IARC p53 database.RhoGTPases and p53 are involved in the morphological appearance and interferon-alpha response of hairy cellsFrequent mutations in EGFR, KRAS and TP53 genes in human lung cancer tumors detected by ion torrent DNA sequencing.Hot-spot mutants of p53 core domain evince characteristic local structural changes.The p53R172H mutant does not enhance hepatocellular carcinoma development and progression.MicroRNAs: short non-coding players in cancer chemoresistance.Identification of Genetic Mutations in Human Lung Cancer by Targeted Sequencing.High metallothionein predicts poor survival in glioblastoma multiforme.Cell type-specific inhibition of p53-mediated apoptosis by mdm2.Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutantMicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of functionPrognostic significance of p53 overexpression and mutation in colorectal adenocarcinomasEffects of p53 mutants derived from lung carcinomas on the p53-responsive element (p53RE) of the MDM2 gene.Nuclear accumulation of p53 correlates significantly with clinical features and inversely with the expression of the cyclin-dependent kinase inhibitor p21(WAF1/CIP1) in pancreatic cancerMutations in the DNA-binding codons of TP53, which are associated with decreased expression of TRAILreceptor-2, predict for poor survival in diffuse large B-cell lymphoma.Activities and response to DNA damage of latent and active sequence-specific DNA binding forms of mouse p53.p21(WAF1/CIP1) expression in stage I cutaneous malignant melanoma: its relationship with p53, cell proliferation and survivalDetection of p73 antibodies in patients with various types of cancer: immunological characterization.Bcl-2/Bax protein ratio predicts 5-fluorouracil sensitivity independently of p53 status.Specific interaction of mutant p53 with regions of matrix attachment region DNA elements (MARs) with a high potential for base-unpairing.Downregulation of p21/WAF1 is related to advanced and dedifferentiated laryngeal squamous cell carcinomaTP53: an oncogene in disguise.A nanobody modulates the p53 transcriptional program without perturbing its functional architectureNFκB and STAT3 synergistically activate the expression of FAT10, a gene counteracting the tumor suppressor p53.Adenovirus type 12-induced fragility of the human RNU2 locus requires p53 function.Regulation of Cdc42-mediated morphological effects: a novel function for p53.A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosisTranscriptional activation by p53 of the human type IV collagenase (gelatinase A or matrix metalloproteinase 2) promoter.
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P2860
Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
Analysis of the most represent ...... ibition of cell proliferation.
@en
type
label
Analysis of the most represent ...... ibition of cell proliferation.
@en
prefLabel
Analysis of the most represent ...... ibition of cell proliferation.
@en
P2093
P2860
P1433
P1476
Analysis of the most represent ...... hibition of cell proliferation
@en
P2093
P2860
P304
P356
10.1002/J.1460-2075.1994.TB06656.X
P407
P577
1994-08-01T00:00:00Z