A novel germ line juxtamembrane Met mutation in human gastric cancer.
about
Interplay between scatter factor receptors and B plexins controls invasive growthStructural characterization of autoinhibited c-Met kinase produced by coexpression in bacteria with phosphatase.Targeting the hepatocyte growth factor-cMET axis in cancer therapyThe MET axis as a therapeutic target.Understanding and Targeting MET Signaling in Solid Tumors - Are We There Yet?Biomarker development in MET-targeted therapyMolecular alterations in gastric cancer with special reference to the early-onset subtypeClinical significance of MET in gastric cancerMET: a critical player in tumorigenesis and therapeutic targetAbl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and MotilityPhase II study evaluating 2 dosing schedules of oral foretinib (GSK1363089), cMET/VEGFR2 inhibitor, in patients with metastatic gastric cancerBiology of MET: a double life between normal tissue repair and tumor progressionMet-Independent Hepatocyte Growth Factor-mediated regulation of cell adhesion in human prostate cancer cells.A putative pH-dependent nuclear localization signal in the juxtamembrane region of c-MetComparison of gene-expression profiles between diffuse- and intestinal-type gastric cancers using a genome-wide cDNA microarray.Molecular mechanisms of activating c-MET in KSHV+ primary effusion lymphoma.Heat-shock protein 27 (HSP27, HSPB1) is up-regulated by MET kinase inhibitors and confers resistance to MET-targeted therapy.Met degradation by SAIT301, a Met monoclonal antibody, reduces the invasion and migration of nasopharyngeal cancer cells via inhibition of EGR-1 expression.MET aberrations and c-MET inhibitors in patients with gastric and esophageal cancers in a phase I unit.Germline met mutations in mice reveal mutation- and background-associated differences in tumor profiles.Valproic acid, targets papillary thyroid cancer through inhibition of c-Met signalling pathwayHGF/MET-directed therapeutics in gastroesophageal cancer: a review of clinical and biomarker development.MET receptor sequence variants R970C and T992I lack transforming capacity.Identification of DNA methylation changes associated with human gastric cancer.Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation.The Hepatocyte Growth Factor Receptor: Structure, Function and Pharmacological Targeting in CancerA novel multipurpose monoclonal antibody for evaluating human c-Met expression in preclinical and clinical settings.Targeting MET Amplification as a New Oncogenic Driver.Dysregulation of Met receptor tyrosine kinase activity in invasive tumorsEpigallocatechin-3-gallate inhibits paracrine and autocrine hepatocyte growth factor/scatter factor-induced tumor cell migration and invasion.Comparison of global gene expression of gastric cardia and noncardia cancers from a high-risk population in chinaCurrent status of novel agents in advanced gastroesophageal adenocarcinoma.Role of genetic polymorphisms in tumour angiogenesisExpression and clinical significance of c-Met in advanced esophageal squamous cell carcinoma.A novel isoform of met receptor tyrosine kinase blocks hepatocyte growth factor/Met signaling and stimulates skeletal muscle cell differentiation.The role of the c-Met pathway in lung cancer and the potential for targeted therapy.Clinical significance of hepatocyte growth factor/c-Met expression in the assessment of gastric cancer progression.Functional consequence of the MET-T1010I polymorphism in breast cancerEarly clinical development of ARQ 197, a selective, non-ATP-competitive inhibitor targeting MET tyrosine kinase for the treatment of advanced cancers.The c-Met Tyrosine Kinase Inhibitor JNJ-38877605 Causes Renal Toxicity through Species-Specific Insoluble Metabolite Formation
P2860
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P2860
A novel germ line juxtamembrane Met mutation in human gastric cancer.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
A novel germ line juxtamembrane Met mutation in human gastric cancer.
@en
type
label
A novel germ line juxtamembrane Met mutation in human gastric cancer.
@en
prefLabel
A novel germ line juxtamembrane Met mutation in human gastric cancer.
@en
P2093
P356
P1433
P1476
A novel germ line juxtamembrane Met mutation in human gastric cancer.
@en
P2093
Jennings B
Vande Woude GF
P2888
P304
P356
10.1038/SJ.ONC.1203874
P407
P50
P577
2000-10-01T00:00:00Z
P5875
P6179
1026741911