Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma - Wikidata - awgldk - TriplyDB

Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma

Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma

http://www.wikidata.org/entity/Q41010294

about

Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland Hes1 potentiates T cell lymphomagenesis by up-regulating a subset of notch target genes.Notch3/Jagged1 circuitry reinforces notch signaling and sustains T-ALL Role of STRAP in regulating GSK3β function and Notch3 stabilization.Repression of Ccr9 transcription in mouse T lymphocyte progenitors by the Notch signaling pathway.Notch Signaling in T-Cell Development and T-ALL Notch regulation of lymphocyte development and function.Notch1-dependent lymphomagenesis is assisted by but does not essentially require pre-TCR signaling Notch signaling in T-cell acute lymphoblastic leukemia.Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia.Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1 Notch signaling in leukemia.A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis.Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression.Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A.NOTCH and phosphatidylinositide 3-kinase/phosphatase and tensin homolog deleted on chromosome ten/AKT/mammalian target of rapamycin (mTOR) signaling in T-cell development and T-cell acute lymphoblastic leukemia.Notch3 and the Notch3-upregulated RNA-binding protein HuD regulate Ikaros alternative splicing.Identification of novel Notch target genes in T cell leukaemia.Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia.Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism.Notch1 promotes survival of E2A-deficient T cell lymphomas through pre-T cell receptor-dependent and -independent mechanisms.Loss of RASGRP1 in humans impairs T-cell expansion leading to Epstein-Barr virus susceptibility.NOTCH3 Intracellular Domain Regulates Transcription

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Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma

http://www.wikidata.org/entity/Q41010294

description

2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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2003年论文

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2003年论文

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name

Pre-TCR-triggered ERK signalli ...... Notch3-induced T-cell lymphoma

@en

type

label

Pre-TCR-triggered ERK signalli ...... Notch3-induced T-cell lymphoma

@en

prefLabel

Pre-TCR-triggered ERK signalli ...... Notch3-induced T-cell lymphoma

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Pre-TCR-triggered ERK signalli ...... Notch3-induced T-cell lymphoma

@en

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Alberto Gulino

http://www.w3.org/2001/XMLSchema#string

Antonio F Campese

http://www.w3.org/2001/XMLSchema#string

Claudio Talora

http://www.w3.org/2001/XMLSchema#string

Diana Bellavia

http://www.w3.org/2001/XMLSchema#string

Harald von Boehmer

http://www.w3.org/2001/XMLSchema#string

Isabella Screpanti

http://www.w3.org/2001/XMLSchema#string

Luigi Frati

http://www.w3.org/2001/XMLSchema#string

Manuela Groppioni

http://www.w3.org/2001/XMLSchema#string

Monica Pascucci

http://www.w3.org/2001/XMLSchema#string

Saula Checquolo

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P2860

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

HASH-1 and E2-2 are expressed in human neuroblastoma cells and form a functional complex

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

Notch signaling: cell fate control and signal integration in development

Notch signaling in cancer

Thymocyte development in early growth response gene 1-deficient mice

Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade.

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.

Disruption of pre-TCR expression accelerates lymphomagenesis in E2A-deficient mice

The function of E- and Id proteins in lymphocyte development.

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1067-1072

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10.1038/SJ.EMBOR.7400013

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11

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4

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14566327

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1326383

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