Frequency of Spontaneous Resistance to Peptide Deformylase Inhibitor GSK1322322 in Haemophilus influenzae, Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae.

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Gut microbiota, metabolites and host immunity.Lack of formylated methionyl-tRNA has pleiotropic effects on Bacillus subtilis.Antibiotics Development and the Emergence of Resistance: Clinical Pharmacology to the Rescue.

P2860

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P2860

Frequency of Spontaneous Resistance to Peptide Deformylase Inhibitor GSK1322322 in Haemophilus influenzae, Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae.

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2015 nî lūn-bûn

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2015年の論文

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Frequency of Spontaneous Resis ...... and Streptococcus pneumoniae.

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Frequency of Spontaneous Resis ...... and Streptococcus pneumoniae.

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Frequency of Spontaneous Resis ...... and Streptococcus pneumoniae.

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Frequency of Spontaneous Resis ...... and Streptococcus pneumoniae.

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Anne Windau

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David J Holmes

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Deborah Butler

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Jason Pizzollo

http://www.w3.org/2001/XMLSchema#string

Jianzhong Huang

http://www.w3.org/2001/XMLSchema#string

Karen Ingraham

http://www.w3.org/2001/XMLSchema#string

Karen O'Dwyer

http://www.w3.org/2001/XMLSchema#string

Kelly Aubart

http://www.w3.org/2001/XMLSchema#string

Linda A Miller

http://www.w3.org/2001/XMLSchema#string

Lynn McCloskey

http://www.w3.org/2001/XMLSchema#string

P2860

Antibiotic Activity and Characterization of BB-3497, a Novel Peptide Deformylase Inhibitor

Crystal structure of type II peptide deformylase from Staphylococcus aureus

Understanding the origins of time-dependent inhibition by polypeptide deformylase inhibitors

Structure of crystalline Escherichia coli methionyl-tRNA(f)Met formyltransferase: comparison with glycinamide ribonucleotide formyltransferase

Crystal structure of the Escherichia coli peptide deformylase

Peptide deformylase in Staphylococcus aureus: resistance to inhibition is mediated by mutations in the formyltransferase gene

Reduced susceptibility of Haemophilus influenzae to the peptide deformylase inhibitor LBM415 can result from target protein overexpression due to amplified chromosomal def gene copy number.

Comparative antimicrobial characterization of LBM415 (NVP PDF-713), a new peptide deformylase inhibitor of clinical importance.

Resistance of Streptococcus pneumoniae to deformylase inhibitors is due to mutations in defB.

Deformylation and protein biosynthesis.

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10.1128/AAC.00484-15

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English

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Frequency of Spontaneous Resistance to Peptide Deformylase Inhibitor GSK1322322 in Haemophilus influenzae, Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae.

about

P2860

P2860

Frequency of Spontaneous Resistance to Peptide Deformylase Inhibitor GSK1322322 in Haemophilus influenzae, Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae.

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