Role of the AcrAB-TolC efflux pump in determining susceptibility of Haemophilus influenzae to the novel peptide deformylase inhibitor LBM415.
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Efflux-mediated drug resistance in bacteria: an updateNew antibiotic molecules: bypassing the membrane barrier of gram negative bacteria increases the activity of peptide deformylase inhibitorsFmt bypass in Pseudomonas aeruginosa causes induction of MexXY efflux pump expressionReduced susceptibility of Haemophilus influenzae to the peptide deformylase inhibitor LBM415 can result from target protein overexpression due to amplified chromosomal def gene copy number.Squalamine: an appropriate strategy against the emergence of multidrug resistant gram-negative bacteria?Efflux pumps as antimicrobial resistance mechanisms.Peptide deformylase inhibitors as potent antimycobacterial agents.The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.Drug forecast - the peptide deformylase inhibitors as antibacterial agents.Antibiotic efflux pumps in Gram-negative bacteria: the inhibitor response strategy.Double trouble: medical implications of genetic duplication and amplification in bacteria.Inhibition of chlamydial infection in the genital tract of female mice by topical application of a peptide deformylase inhibitorApplication of microarray and functional-based screening methods for the detection of antimicrobial resistance genes in the microbiomes of healthy humans.Frequency of Spontaneous Resistance to Peptide Deformylase Inhibitor GSK1322322 in Haemophilus influenzae, Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae.Activity of LBM415 compared to those of 11 other agents against Haemophilus species.First characterization of heterogeneous resistance to imipenem in invasive nontypeable Haemophilus influenzae isolates.Single nucleotide polymorphisms in genes encoding penicillin-binding proteins in β-lactamase-negative ampicillin-resistant Haemophilus influenzae in Japan.XCC2366, A Gene Encoding A Putative TetR Family Transcriptional Regulator, is Required for Acriflavin Resistance and Virulence of Xanthomonas campestris pv. campestris.Transcriptional Modulation of Penicillin-Binding Protein 1b, Outer Membrane Protein P2 and Efflux Pump (AcrAB-TolC) during Heat Stress Is Correlated to Enhanced Bactericidal Action of Imipenem on Non-typeable Haemophilus influenzae.Pharmacokinetics and unexpected safety issues of LBM415, a novel oral peptide deformylase inhibitor.
P2860
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P2860
Role of the AcrAB-TolC efflux pump in determining susceptibility of Haemophilus influenzae to the novel peptide deformylase inhibitor LBM415.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Role of the AcrAB-TolC efflux ...... deformylase inhibitor LBM415.
@en
type
label
Role of the AcrAB-TolC efflux ...... deformylase inhibitor LBM415.
@en
prefLabel
Role of the AcrAB-TolC efflux ...... deformylase inhibitor LBM415.
@en
P2093
P2860
P1476
Role of the AcrAB-TolC efflux ...... deformylase inhibitor LBM415.
@en
P2093
Beat Weidmann
Charles R Dean
Denis M Daigle
JoAnn L Dzink-Fox
Karl E Dean
Kathryn R Bracken
Neil S Ryder
Rakesh Jain
Shubha Narayan
Xiaoling Puyang
P2860
P304
P356
10.1128/AAC.49.8.3129-3135.2005
P407
P577
2005-08-01T00:00:00Z