Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation.
about
CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machineryThreshold-controlled ubiquitination of the EGFR directs receptor fateAnalysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interferenceUbiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosisGrowth factors induce differential phosphorylation profiles of the Hrs-STAM complex: a common node in signalling networks with signal-specific propertiesDifferential requirements for AP-2 in clathrin-mediated endocytosisFunctional Integration of the Conserved Domains of Shoc2 ScaffoldThe ubiquitin/proteasome system mediates entry and endosomal trafficking of Kaposi's sarcoma-associated herpesvirus in endothelial cellsLipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptorsProteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pitsCbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pitsClathrin-independent endocytosis of ErbB2 in geldanamycin-treated human breast cancer cells.Epsin 1 is a cargo-specific adaptor for the clathrin-mediated endocytosis of the influenza virus.Ligands for clathrin-mediated endocytosis are differentially sorted into distinct populations of early endosomesGrowth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis.Characterization of the localization and function of NECAP 1 in neurons.Adaptor protein Ruk/CIN85 is associated with a subset of COPI-coated membranes of the Golgi complex.The ubiquitination code: a signalling problem.Clathrin-independent pathways of endocytosis.D-Cbl binding to Drk leads to dose-dependent down-regulation of EGFR signaling and increases receptor-ligand endocytosis.Clathrin-independent endocytosis of ubiquitinated cargosc-Cbl facilitates endocytosis and lysosomal degradation of cystic fibrosis transmembrane conductance regulator in human airway epithelial cellsMet/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation.The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs.Molecular Mechanisms that Regulate Epidermal Growth Factor Receptor InactivationARAP1 regulates endocytosis of EGFR.Targeting the EGFR signaling pathway in cancer therapy.HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold.Shiga toxin regulates its entry in a Syk-dependent manner.Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.Activation of EGFR, HER2 and HER3 by neurotensin/neurotensin receptor 1 renders breast tumors aggressive yet highly responsive to lapatinib and metformin in mice.Activation of p38 mitogen-activated protein kinase promotes epidermal growth factor receptor internalization.Endocytosis and intracellular trafficking of ErbBs.Molecular mechanisms of cigarette smoke-induced proliferation of lung cells and prevention by vitamin C.Epidermal growth factor receptor exposed to cigarette smoke is aberrantly activated and undergoes perinuclear trafficking.The signaling and transformation potency of the overexpressed HER2 protein is dependent on the normally-expressed EGFR.Human proteome-scale structural modeling of E2-E3 interactions exploiting interface motifs.The Ankrd 13 family of UIM-bearing proteins regulates EGF receptor endocytosis from the plasma membrane.EGF receptor ubiquitination is not necessary for its internalization.
P2860
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P2860
Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Epidermal growth factor recept ...... t receptor polyubiquitylation.
@en
Epidermal growth factor recept ...... t receptor polyubiquitylation.
@nl
type
label
Epidermal growth factor recept ...... t receptor polyubiquitylation.
@en
Epidermal growth factor recept ...... t receptor polyubiquitylation.
@nl
prefLabel
Epidermal growth factor recept ...... t receptor polyubiquitylation.
@en
Epidermal growth factor recept ...... t receptor polyubiquitylation.
@nl
P1433
P1476
Epidermal growth factor recept ...... t receptor polyubiquitylation.
@en
P2093
Alexander Sorkin
Xuejun Jiang
P304
P356
10.1034/J.1600-0854.2003.T01-1-00109.X
P577
2003-08-01T00:00:00Z