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Three-dimensional structure of kynureninase from Pseudomonas fluorescensThe Second Enzyme in Pyrrolnitrin Biosynthetic Pathway Is Related to the Heme-Dependent Dioxygenase Superfamily †Crystal structure of the Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex: insights into the molecular basis of kynureninase substrate specificityThe crystal structure of the Pseudomonas dacunhae aspartate-beta-decarboxylase dodecamer reveals an unknown oligomeric assembly for a pyridoxal-5'-phosphate-dependent enzymeConformational changes and loose packing promote E. coli Tryptophanase cold labilityCrystallographic Snapshots of Tyrosine Phenol-lyase Show That Substrate Strain Plays a Role in C–C Bond CleavageThe crystal structure of Citrobacter freundii tyrosine phenol-lyase complexed with 3-(4'-hydroxyphenyl)propionic acid, together with site-directed mutagenesis and kinetic analysis, demonstrates that arginine 381 is required for substrate specificityAsymmetric kinetics of protein structural changes.Structure and mechanism of kynureninase.Mass defect labeling of cysteine for improving peptide assignment in shotgun proteomic analyses.A matrix-assisted laser desorption/ionization compatible reagent for tagging tryptophan residues.Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4.Effects of hydrostatic pressure on the conformational equilibrium of tryptophan synthase from Salmonella typhimurium.A redox-active FKBP-type immunophilin functions in accumulation of the photosystem II supercomplex in Arabidopsis thaliana.Mutation of Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase at Trp-110 affects stereoselectivity of aromatic ketone reduction.A Mannose Family Phosphotransferase System Permease and Associated Enzymes Are Required for Utilization of Fructoselysine and Glucoselysine in Salmonella enterica Serovar Typhimurium.Benzoate decreases the binding of cis,cis-muconate to the BenM regulator despite the synergistic effect of both compounds on transcriptional activation.Tyrosine phenol-lyase and tryptophan indole-lyase encapsulated in wet nanoporous silica gels: Selective stabilization of tertiary conformationsSalmonella utilizes D-glucosaminate via a mannose family phosphotransferase system permease and associated enzymes.The role of substrate strain in the mechanism of the carbon-carbon lyases.The role of glutamic acid-69 in the activation of Citrobacter freundii tyrosine phenol-lyase by monovalent cations.Chemistry and diversity of pyridoxal-5'-phosphate dependent enzymes.Inhibition of tyrosine phenol-lyase by tyrosine homologues.Regioselective nitration of N(alpha),N(1)-bis(trifluoroacetyl)-L-tryptophan methyl ester: efficient synthesis of 2-nitro and 6-nitro-N-trifluoroacetyl-L-tryptophan methyl ester.Dopamine-B-hydroxylase: suicide inhibition by the novel olefinic substrate, 1-phenyl-1-aminomethylethene.Pressure and temperature jump relaxation kinetics of the conformational change in Salmonella typhimurium tryptophan synthase L-serine complex: large activation compressibility and heat capacity changes demonstrate the contribution of solvation.19F-NMR reveals metal and operator-induced allostery in MerR.Hydrostatic pressure affects the conformational equilibrium of Salmonella typhimurium tryptophan synthase.Substituent effects on the reaction of beta-benzoylalanines with Pseudomonas fluorescens kynureninase.Threonine-124 and phenylalanine-448 in Citrobacter freundii tyrosine phenol-lyase are necessary for activity with L-tyrosine.I86A/C295A mutant secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus has broadened substrate specificity for aryl ketones.Insights into the mechanism of Pseudomonas dacunhae aspartate beta-decarboxylase from rapid-scanning stopped-flow kinetics.Stopped-flow studies of the reaction of D-tartronate semialdehyde-2-phosphate with human neuronal enolase and yeast enolase 1.The stereospecificity of secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus is partially determined by active site water.Enzymatic synthesis of aza-l-tyrosines.A rare variant at the KYNU gene is associated with kynureninase activity and essential hypertension in the Han Chinese population.Inhibition of tyrosine phenol-lyase from Citrobacter freundii by 2-azatyrosine and 3-azatyrosine.Formation in vitro of hybrid dimers of H463F and Y74F mutant Escherichia coli tryptophan indole-lyase rescues activity with L-tryptophan.Cold-induced enzyme inactivation: how does cooling lead to pyridoxal phosphate-aldimine bond cleavage in tryptophanase?Kinetics and mechanism of superoxide reduction by two-iron superoxide reductase from Desulfovibrio vulgaris.
P50
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P50
description
hulumtues
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researcher
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wetenschapper
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հետազոտող
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name
Robert S. Phillips
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Robert S. Phillips
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Robert S. Phillips
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Robert S. Phillips
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Robert S. Phillips
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type
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Robert S. Phillips
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Robert S. Phillips
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Robert S. Phillips
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Robert S. Phillips
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Robert S. Phillips
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prefLabel
Robert S. Phillips
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Robert S. Phillips
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Robert S. Phillips
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Robert S. Phillips
@nl
Robert S. Phillips
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P106
P1153
7404240886
P21
P31
P496
0000-0001-8710-562X