Role of hyperthermia in the protective action of clomethiazole against MDMA ('ecstasy')-induced neurodegeneration, comparison with the novel NMDA channel blocker AR-R15896AR.
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Lost in translation: preclinical studies on 3,4-methylenedioxymethamphetamine provide information on mechanisms of action, but do not allow accurate prediction of adverse events in humansA study of the mechanisms involved in the neurotoxic action of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') on dopamine neurones in mouse brainNeurotoxicity of methamphetamine and 3,4-methylenedioxymethamphetamineNeurotoxicity of drugs of abuse--the case of methylenedioxyamphetamines (MDMA, ecstasy), and amphetamines.MDMA-induced loss of parvalbumin interneurons within the dentate gyrus is mediated by 5HT2A and NMDA receptorsInhibition of the dorsomedial hypothalamus, but not the medullary raphe pallidus, decreases hyperthermia and mortality from MDMA given in a warm environment.MDMA-induced neurotoxicity: long-term effects on 5-HT biosynthesis and the influence of ambient temperature.Protection against 3,4-methylenedioxymethamphetamine-induced neurodegeneration produced by glutathione depletion in rats is mediated by attenuation of hyperthermia.Studies on the role of dopamine in the degeneration of 5-HT nerve endings in the brain of Dark Agouti rats following 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy') administration.Enhancement of 3,4-methylenedioxymethamphetamine neurotoxicity by the energy inhibitor malonate.On the protection against methamphetamine-induced neurotoxicity by benzamide, a PARP inhibitor.Microglial and astroglial activation by 3,4-methylenedioxymethamphetamine (MDMA) in mice depends on S(+) enantiomer and is associated with an increase in body temperature and motility.Metformin Prevented Dopaminergic Neurotoxicity Induced by 3,4-Methylenedioxymethamphetamine Administration.Mazindol attenuates the 3,4-methylenedioxymethamphetamine-induced formation of hydroxyl radicals and long-term depletion of serotonin in the striatum.Effects of antihistamines on fenfluramine-induced depletion of indoles in the brain of rats.Memory-related hippocampal functioning in ecstasy and amphetamine users: a prospective fMRI study.Methylenedioxymethamphetamine (MDMA, ‘Ecstasy’): Neurodegeneration versus Neuromodulation.
P2860
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P2860
Role of hyperthermia in the protective action of clomethiazole against MDMA ('ecstasy')-induced neurodegeneration, comparison with the novel NMDA channel blocker AR-R15896AR.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Role of hyperthermia in the pr ...... A channel blocker AR-R15896AR.
@en
Role of hyperthermia in the pr ...... A channel blocker AR-R15896AR.
@nl
type
label
Role of hyperthermia in the pr ...... A channel blocker AR-R15896AR.
@en
Role of hyperthermia in the pr ...... A channel blocker AR-R15896AR.
@nl
prefLabel
Role of hyperthermia in the pr ...... A channel blocker AR-R15896AR.
@en
Role of hyperthermia in the pr ...... A channel blocker AR-R15896AR.
@nl
P2093
P2860
P356
P1476
Role of hyperthermia in the pr ...... A channel blocker AR-R15896AR.
@en
P2093
P2860
P304
P356
10.1038/SJ.BJP.0701859
P407
P577
1998-06-01T00:00:00Z