The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
about
The coding/non-coding overlapping architecture of the gene encoding the Drosophila pseudouridine synthasehNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomeraseDynamic association and localization of human H/ACA RNP proteinsGenetic heterogeneity in autosomal recessive dyskeratosis congenita with one subtype due to mutations in the telomerase-associated protein NOP10The genetics of dyskeratosis congenitaMutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenitaCrystal structure determination and site-directed mutagenesis of the Pyrococcus abyssi aCBF5-aNOP10 complex reveal crucial roles of the C-terminal domains of both proteins in H/ACA sRNP activity.It all comes together at the ends: telomerase structure, function, and biogenesisSmall RNAs with big implications: new insights into H/ACA snoRNA function and their role in human diseaseH/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modificationHow U38, 39, and 40 of Many tRNAs Become the Targets for Pseudouridylation by TruAStructure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNAStructure of H/ACA RNP Protein Nhp2p Reveals Cis/Trans Isomerization of a Conserved Proline at the RNA and Nop10 Binding InterfaceReconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthaseDifferent mechanisms for pseudouridine formation in yeast 5S and 5.8S rRNAs.Structure-function relationships of archaeal Cbf5 during in vivo RNA-guided pseudouridylation.A core-attachment based method to detect protein complexes in PPI networks.The box H/ACA ribonucleoprotein complex: interplay of RNA and protein structures in post-transcriptional RNA modification.Genetic Variations in Telomere Maintenance, with Implications on Tissue Renewal Capacity and Chronic Disease Pathologies.The dyskerin ribonucleoprotein complex as an OCT4/SOX2 coactivator in embryonic stem cells.Comparative study of two box H/ACA ribonucleoprotein pseudouridine-synthases: relation between conformational dynamics of the guide RNA, enzyme assembly and activity.Formation of the conserved pseudouridine at position 55 in archaeal tRNArRNA pseudouridylation defects affect ribosomal ligand binding and translational fidelity from yeast to human cells.The structure and function of small nucleolar ribonucleoproteins.Accurate placement of substrate RNA by Gar1 in H/ACA RNA-guided pseudouridylation.Identification of determinants in the protein partners aCBF5 and aNOP10 necessary for the tRNA:Psi55-synthase and RNA-guided RNA:Psi-synthase activities.RNA-guided isomerization of uridine to pseudouridine--pseudouridylation.Kinetic and thermodynamic characterization of the reaction pathway of box H/ACA RNA-guided pseudouridine formation.How a single protein complex accommodates many different H/ACA RNAs.Substrate recognition by RNA 5-methyluridine methyltransferases and pseudouridine synthases: a structural perspective.Combined in silico and experimental identification of the Pyrococcus abyssi H/ACA sRNAs and their target sites in ribosomal RNAsRNA pseudouridylation: new insights into an old modificationNoncoding RNAs of the H/ACA family.Unveiling substrate RNA binding to H/ACA RNPs: one side fits all.The PUA domain - a structural and functional overview.Genomic context analysis in Archaea suggests previously unrecognized links between DNA replication and translation.Evolutionary perspectives of telomerase RNA structure and function.Variable expression of Dkc1 mutations in miceH/ACA small RNA dysfunctions in disease reveal key roles for noncoding RNA modifications in hematopoietic stem cell differentiation.Insight into the Protein Components of the Box H/ACA RNP
P2860
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P2860
The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
@en
The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
@nl
type
label
The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
@en
The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
@nl
prefLabel
The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
@en
The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
@nl
P2093
P2860
P356
P1476
The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs
@en
P2093
Adrian R Ferré-D'Amaré
Gabriele Varani
Tomoko Hamma
P2860
P2888
P304
P356
10.1038/NSMB1036
P577
2005-11-15T00:00:00Z