2,4-Diarylpyrrolidine-3-carboxylic acids--potent ETA selective endothelin receptor antagonists. 1. Discovery of A-127722.

2,4-Diarylpyrrolidine-3-carboxylic acids--potent ETA selective endothelin receptor antagonists. 1. Discovery of A-127722.

Item
http://www.wikidata.org/entity/Q42555748
ET(B) receptor-deficient rats exhibit reduced contraction to ET-1 despite an increase in ET(A) receptorsEndothelin antagonism in portal hypertensive mice: implications for endothelin receptor-specific signaling in liver disease.Contrasting effects of intervention with ETA and ETB receptor antagonists in hypertension induced by angiotensin II and high-salt dietEffect of ABT-627 (A-147627), a potent selective ET(A) receptor antagonist, on the cardiopulmonary profile of newborn lambs with surgically-induced diaphragmatic hernia.ETA activation mediates angiotensin II-induced infiltration of renal cortical T cells.Endothelin-1 as a master regulator of whole-body Na+ homeostasis.Endothelin A receptor blockade reduces diabetic renal injury via an anti-inflammatory mechanism.Endothelin-1 contributes to the progression of renal injury in sickle cell disease via reactive oxygen speciesSystemic hypertension induced by hepatic overexpression of human preproendothelin-1 in rats.ETA and ETB receptors differentially modulate afferent and efferent arteriolar responses to endothelin.Role of ET-1 receptor binding and [Ca(2+)](i) in contraction of coronary arteries from DOCA-salt hypertensive rats.RhoA-Rho kinase mediates synergistic ET-1 and phenylephrine contraction of rat corpus cavernosum.X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog.ET receptor activation contributes to T cell accumulation in the kidney following ischemia-reperfusion injury
P2860

2,4-Diarylpyrrolidine-3-carboxylic acids--potent ETA selective endothelin receptor antagonists. 1. Discovery of A-127722.

Item
http://www.wikidata.org/entity/Q42555748
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
2,4-Diarylpyrrolidine-3-carbox ...... sts. 1. Discovery of A-127722.
@en
2,4-Diarylpyrrolidine-3-carbox ...... sts. 1. Discovery of A-127722.
@nl
type
label
2,4-Diarylpyrrolidine-3-carbox ...... sts. 1. Discovery of A-127722.
@en
2,4-Diarylpyrrolidine-3-carbox ...... sts. 1. Discovery of A-127722.
@nl
prefLabel
2,4-Diarylpyrrolidine-3-carbox ...... sts. 1. Discovery of A-127722.
@en
2,4-Diarylpyrrolidine-3-carbox ...... sts. 1. Discovery of A-127722.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
2,4-Diarylpyrrolidine-3-carbox ...... sts. 1. Discovery of A-127722.
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698