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In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use.In vitro blood-brain barrier permeability predictions for GABAA receptor modulating piperine analogs.IPEC-J2 MDR1, a Novel High-Resistance Cell Line with Functional Expression of Human P-glycoprotein (ABCB1) for Drug Screening Studies.Sodium caprate transiently opens claudin-5-containing barriers at tight junctions of epithelial and endothelial cells.An electrically tight in vitro blood-brain barrier model displays net brain-to-blood efflux of substrates for the ABC transporters, P-gp, Bcrp and Mrp-1.Evaluating the involvement of cerebral microvascular endothelial Na(+)/K(+)-ATPase and Na(+)-K(+)-2Cl(-) co-transporter in electrolyte fluxes in an in vitro blood-brain barrier model of dehydration.Glutamate Transporters in the Blood-Brain Barrier.Characterization of the L-glutamate clearance pathways across the blood-brain barrier and the effect of astrocytes in an in vitro blood-brain barrier model.Transferrin receptor expression and role in transendothelial transport of transferrin in cultured brain endothelial monolayers.In vitro evidence for the brain glutamate efflux hypothesis: brain endothelial cells cocultured with astrocytes display a polarized brain-to-blood transport of glutamate.Generation of primary cultures of bovine brain endothelial cells and setup of cocultures with rat astrocytesThe insulin receptor is expressed and functional in cultured blood-brain barrier endothelial cells but does not mediate insulin entry from blood to brainTight junctions in the blood-brain barrier promote edema formation and infarct size in stroke - Ambivalent effects of sealing proteinsSemaglutide lowers body weight in rodents via distributed neural pathwaysEffects of oxygen-glucose deprivation (OGD) on barrier properties and mRNA transcript levels of selected marker proteins in brain endothelial cells/astrocyte co-cultures
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description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Hans Christian Helms
@ast
Hans Christian Helms
@en
Hans Christian Helms
@es
Hans Christian Helms
@nl
Hans Christian Helms
@sl
type
label
Hans Christian Helms
@ast
Hans Christian Helms
@en
Hans Christian Helms
@es
Hans Christian Helms
@nl
Hans Christian Helms
@sl
prefLabel
Hans Christian Helms
@ast
Hans Christian Helms
@en
Hans Christian Helms
@es
Hans Christian Helms
@nl
Hans Christian Helms
@sl
P106
P21
P31
P496
0000-0001-6105-1707