about
Spatial and temporal dynamics of two alternatively spliced regulatory factors, lens epithelium-derived growth factor (ledgf/p75) and p52, in the nucleusLens epithelium-derived growth factor: effects on growth and survival of lens epithelial cells, keratinocytes, and fibroblastsTranscriptional regulation of the antioxidant protein 2 gene, a thiol-specific antioxidant, by lens epithelium-derived growth factor to protect cells from oxidative stressTransactivation of involucrin, a marker of differentiation in keratinocytes, by lens epithelium-derived growth factor (LEDGF)The sequence of human retinal S-antigen reveals similarities with alpha-transducinThe sequence of the mouse phosducin-encoding gene and its 5'-flanking regionExpression of extracellular calcium-sensing receptor by human lens epithelial cells.LEDGF, a survival factor, activates stress-related genes.Biosynthesis, characterization, and efficacy in retinal degenerative diseases of lens epithelium-derived growth factor fragment (LEDGF1-326), a novel therapeutic protein.Low glucose under hypoxic conditions induces unfolded protein response and produces reactive oxygen species in lens epithelial cells.Porcine S-antigen: cDNA sequence and expression in retina, ciliary epithelium and iris.S-antigen: from gene to autoimmune uveitis.Role of the unfolded protein response (UPR) in cataract formation.Age-related cataracts: homocysteine coupled endoplasmic reticulum stress and suppression of Nrf2-dependent antioxidant protection.Cholesterol-derived bile acids enhance the chaperone activity of α-crystallins.Detection of cytotoxic anti-LEDGF autoantibodies in atopic dermatitis.LEDGF activation of PKC gamma and gap junction disassembly in lens epithelial cells.Lens epithelium-derived growth factor: neuroprotection on rat retinal damage induced by N-methyl-D-aspartate.LEDGF regulation of alcohol and aldehyde dehydrogenases in lens epithelial cells: stimulation of retinoic acid production and protection from ethanol toxicity.Suppression of experimental autoimmune uveitis in rats by the oral administration of the uveitopathogenic S-antigen fragment or a cross-reactive homologous peptide.Silencing gene therapy for mutant membrane, secretory, and lipid proteins in retinitis pigmentosa (RP).Enhancement of S-antigen and its mRNA in the irides of uveitic patients.Cataracts: role of the unfolded protein response.Arrestin and phosducin are expressed in a small number of brain cells.S-antigen from the rat retina and pineal gland have identical sequences.Cloning, high level-expression and characterization of human lens thioltransferaseScale-up methodology for the preparative purification of peptide MAssignment of the S-antigen gene (SAG) to human chromosome 2q24-q37Immunization with recombinant Escherichia coli expressing retinal S-antigen-induced experimental autoimmune uveitis (EAU) in Lewis ratsOligopeptides of three to five residues derived from uveitopathogenic sites of retinal S-antigen induce experimental autoimmune uveitis (EAU) in Lewis ratsCone cells fail to develop normally in transgenic mice showing ablation of rod photoreceptor cellsCorticosteroids enhance S-antigen expression in nonretinal ocular tissues of rats with experimental autoimmune uveitisTranscription factor IID probes localize a single gene to the proximal region of mouse chromosome 17Lens epithelium-derived growth factor relieves transforming growth factor-beta1-induced transcription repression of heat shock proteins in human lens epithelial cellsAnti-beta-crystallin antibodies (mouse) or sera from humans with age-related cataract are cytotoxic for lens epithelial cells in cultureThe 5' flanking regions of IRBP and arrestin have promoter activity in primary embryonic chicken retina cell culturesOral administration of lens homogenate suppresses antibody production in mice injected with beta-crystallin emulsified in CFACloning, high level-expression and characterization of human lens thioltransferaseLEDGF binds to heat shock and stress-related element to activate the expression of stress-related genesCellular immune response to retinal S-antigen and interphotoreceptor retinoid-binding protein fragments in Eales' disease patients
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Toshimichi Shinohara
@ast
Toshimichi Shinohara
@en
Toshimichi Shinohara
@es
Toshimichi Shinohara
@nl
Toshimichi Shinohara
@sl
type
label
Toshimichi Shinohara
@ast
Toshimichi Shinohara
@en
Toshimichi Shinohara
@es
Toshimichi Shinohara
@nl
Toshimichi Shinohara
@sl
prefLabel
Toshimichi Shinohara
@ast
Toshimichi Shinohara
@en
Toshimichi Shinohara
@es
Toshimichi Shinohara
@nl
Toshimichi Shinohara
@sl
P106
P1153
7202958417
P21
P31
P496
0000-0002-7197-9039
P569
2000-01-01T00:00:00Z