The Dbf4 motif C zinc finger promotes DNA replication and mediates resistance to genotoxic stress.
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Interactions of the human MCM-BP protein with MCM complex components and Dbf4Saccharomyces cerevisiae Dbf4 Has Unique Fold Necessary for Interaction with Rad53 KinaseCrystal structure of human CDC7 kinase in complex with its activator DBF4Mechanisms Governing DDK Regulation of the Initiation of DNA ReplicationA quantitative model of the initiation of DNA replication in Saccharomyces cerevisiae predicts the effects of system perturbations.Phosphorylation of Mcm2 modulates Mcm2-7 activity and affects the cell's response to DNA damageConcerted activities of Mcm4, Sld3, and Dbf4 in control of origin activation and DNA replication fork progressionDbf4: the whole is greater than the sum of its partsGlobal mitotic phosphorylation of C2H2 zinc finger protein linker peptidesA synthetic human kinase can control cell cycle progression in budding yeast.Dbf4 and Cdc7 proteins promote DNA replication through interactions with distinct Mcm2-7 protein subunits.A novel non-canonical forkhead-associated (FHA) domain-binding interface mediates the interaction between Rad53 and Dbf4 proteins.Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer.Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing.
P2860
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P2860
The Dbf4 motif C zinc finger promotes DNA replication and mediates resistance to genotoxic stress.
description
2010 nî lūn-bûn
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name
The Dbf4 motif C zinc finger p ...... esistance to genotoxic stress.
@en
The Dbf4 motif C zinc finger p ...... esistance to genotoxic stress.
@nl
type
label
The Dbf4 motif C zinc finger p ...... esistance to genotoxic stress.
@en
The Dbf4 motif C zinc finger p ...... esistance to genotoxic stress.
@nl
prefLabel
The Dbf4 motif C zinc finger p ...... esistance to genotoxic stress.
@en
The Dbf4 motif C zinc finger p ...... esistance to genotoxic stress.
@nl
P2093
P356
P1433
P1476
The Dbf4 motif C zinc finger p ...... esistance to genotoxic stress.
@en
P2093
Ajai A Prasad
Darryl R Jones
Philip K Chan
P304
P356
10.4161/CC.9.10.11752
P577
2010-05-15T00:00:00Z