Mitochondrial processing of newly synthesized steroidogenic acute regulatory protein (StAR), but not total StAR, mediates cholesterol transfer to cytochrome P450 side chain cleavage enzyme in adrenal cells.
about
In a mouse model relevant for post-traumatic stress disorder, selective brain steroidogenic stimulants (SBSS) improve behavioral deficits by normalizing allopregnanolone biosynthesis.The molecular biology, biochemistry, and physiology of human steroidogenesis and its disordersNonclassic congenital lipoid adrenal hyperplasia: a new disorder of the steroidogenic acute regulatory protein with very late presentation and normal male genitaliaACTH Action on StAR BiologycAMP-dependent posttranscriptional regulation of steroidogenic acute regulatory (STAR) protein by the zinc finger protein ZFP36L1/TIS11bBinding domain-driven intracellular trafficking of sterols for synthesis of steroid hormones, bile acids and oxysterolsPulmonary surfactant pathophysiology: current models and open questionsTranslocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesisACTH-induced nucleocytoplasmic translocation of salt-inducible kinase. Implication in the protein kinase A-activated gene transcription in mouse adrenocortical tumor cellsStAR expression and the long-term aldosterone response to high-potassium diet in Wistar-Kyoto and spontaneously hypertensive ratsSystemic administration of alcohol to adult rats inhibits leydig cell activity: Time course of effect and role of nitric oxideMolecular modeling and structure-based thermodynamic analysis of the StAR protein.STARD3 mediates endoplasmic reticulum-to-endosome cholesterol transport at membrane contact sitesA mitochondrial kinase complex is essential to mediate an ERK1/2-dependent phosphorylation of a key regulatory protein in steroid biosynthesis.Identification of a dynamic mitochondrial protein complex driving cholesterol import, trafficking, and metabolism to steroid hormonesMitochondrial fusion and ERK activity regulate steroidogenic acute regulatory protein localization in mitochondriaATP synthesis, mitochondrial function, and steroid biosynthesis in rodent primary and tumor Leydig cellsA computational model of the hypothalamic: pituitary: gonadal axis in female fathead minnows (Pimephales promelas) exposed to 17α-ethynylestradiol and 17β-trenbolone.Estradiol modulates translocator protein (TSPO) and steroid acute regulatory protein (StAR) via protein kinase A (PKA) signaling in hypothalamic astrocytesSteroidogenic acute regulatory protein-binding protein cloned by a yeast two-hybrid system.Early steps in steroidogenesis: intracellular cholesterol trafficking.Ethanol induction of steroidogenesis in rat adrenal and brain is dependent upon pituitary ACTH release and de novo adrenal StAR synthesisThe adaptive response of adult rat Leydig cells to repeated immobilization stress: the role of protein kinase A and steroidogenic acute regulatory protein.Mitochondrial protein import and the genesis of steroidogenic mitochondriaNovel androstenetriol interacts with the mitochondrial translocator protein and controls steroidogenesis.In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine.High-flux mitochondrial cholesterol trafficking, a specialized function of the adrenal cortexDecreased cytochrome c oxidase IV expression reduces steroidogenesisStAR Protein Stability in Y1 and Kin-8 Mouse Adrenocortical Cells.Stimulation of StAR expression by cAMP is controlled by inhibition of highly inducible SIK1 via CRTC2, a co-activator of CREB.Adrenal androgens and androgen precursors-definition, synthesis, regulation and physiologic actions.Control of aldosterone secretion: a model for convergence in cellular signaling pathways.Angiotensin II-dependent transcriptional activation of human steroidogenic acute regulatory protein gene by a 25-kDa cAMP-responsive element modulator protein isoform and Yin Yang 1.The importance of biological oscillators for hypothalamic-pituitary-adrenal activity and tissue glucocorticoid response: coordinating stress and neurobehavioural adaptation.In search of the function of the peripheral-type benzodiazepine receptor.Sickling cells, cyclic nucleotides, and protein kinases: the pathophysiology of urogenital disorders in sickle cell anemia.cAMP stimulation of StAR expression and cholesterol metabolism is modulated by co-expression of labile suppressors of transcription and mRNA turnoverRole of the steroidogenic acute regulatory protein in health and disease.Complex role of the mitochondrial targeting signal in the function of steroidogenic acute regulatory protein revealed by bacterial artificial chromosome transgenesis in vivo.SNARE-Mediated Cholesterol Movement to Mitochondria Supports Steroidogenesis in Rodent Cells.
P2860
Q24605563-51EFCB85-41C9-41C9-A40E-42FDFAB98752Q24613957-D83A8315-34FE-421D-8618-7A8E2CABA9FCQ24673327-D8AAC0AC-0EEF-4BDA-B492-C2F21B4C9F20Q28073213-32FE7CE2-1786-4B69-B69E-20E11F551B37Q28118974-62813C62-EBEA-46BA-B0F1-ABDBCE1DB74EQ28241207-D2E573AB-5F7F-463D-BE12-7F0848AEFFD2Q28285439-DA37B87E-D112-4EAB-BA73-1F909658B174Q28301125-755F0878-5E93-4015-92EE-D72732F13ED8Q28509981-D02D303E-E700-46F5-8BA5-8F18C4726087Q28573790-52BBFA20-FD4D-4FC9-80B3-72251C80863EQ28579680-C88C6B19-943D-442B-89DB-FC026DD5F7D8Q30164956-797278DF-BDD0-4DAB-97EF-FD8B820D4E34Q30274625-7EF4C58A-1CB5-4075-AFFB-E0ACA7079E16Q33314909-82A69A34-E47D-42A9-8E47-227B8150672FQ33636284-4A018DEF-C8ED-468E-AB22-8C90CF10367EQ33778923-808ED6D9-B58B-4E1B-AB96-D3C099213D05Q33791705-BF65E3D1-6A2B-421C-8D1F-8D14D7040114Q33890617-62944FCB-04D9-4C2B-97C4-BCF3C70B2AA0Q33901187-F4879170-DDB1-4C47-B963-279D4F0E36BEQ34221139-5FE142EE-6AD7-44DD-9DFE-3521A524B5F3Q34221799-67924E48-86E2-40F9-A11D-8C25C484086AQ34568770-8F0DF8C5-324A-4FA5-BC99-E162D4AE871EQ34657176-52C951D3-4179-4DA5-9F42-B4C70F21C3D2Q34672406-B6AB5983-EBB1-47CF-ABCC-EDD9DFA56498Q34684671-03398F15-0DB6-4EF0-8A43-BDC9D32E47F2Q34763151-9C2E5FB5-834D-4D5D-8AE7-F3EFB7F27438Q34799099-D6F11887-48D7-4545-93DB-1CD97BD3D553Q35122905-9AB954E8-3F42-4AB0-9BAA-D61E638340BFQ35237411-CC495DA2-7402-4A0C-9DC7-F85E4AD2F084Q35563077-DBF24DCF-FBC5-4C6C-829E-9ECFB00CD454Q35624417-BABABEC1-92DF-4FF1-A151-0FC44577D8F6Q35715226-26793543-1D9A-46F3-9F66-1E1620A2BE5BQ35762734-EB2C5381-B0E9-4C61-AC68-8F1003A61974Q35964417-9864E4A1-7EAA-4838-9E26-B31F4A7A0896Q36018193-C7BE38B9-C92B-4E0A-B3A2-1666FC148759Q36056143-B600964F-D867-483E-9A80-4AE2A48F7352Q36114612-13DC176E-D8B8-44FE-AFE8-BD64E651F76AQ36447481-2C1C6C25-4F3F-4E7D-891D-C40956A9C4E7Q36512421-C5DDB22F-936E-44E9-95C8-4A1B71DDF245Q36688121-226C2669-0030-4062-83F3-ADD969C8481F
P2860
Mitochondrial processing of newly synthesized steroidogenic acute regulatory protein (StAR), but not total StAR, mediates cholesterol transfer to cytochrome P450 side chain cleavage enzyme in adrenal cells.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Mitochondrial processing of ne ...... avage enzyme in adrenal cells.
@en
Mitochondrial processing of ne ...... avage enzyme in adrenal cells.
@nl
type
label
Mitochondrial processing of ne ...... avage enzyme in adrenal cells.
@en
Mitochondrial processing of ne ...... avage enzyme in adrenal cells.
@nl
prefLabel
Mitochondrial processing of ne ...... avage enzyme in adrenal cells.
@en
Mitochondrial processing of ne ...... avage enzyme in adrenal cells.
@nl
P2093
P2860
P356
P1476
Mitochondrial processing of ne ...... avage enzyme in adrenal cells.
@en
P2093
P2860
P304
46583-46596
P356
10.1074/JBC.M107815200
P407
P577
2001-09-28T00:00:00Z