Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines.
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MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancerExtreme growth factor signalling can promote oestrogen receptor-alpha loss: therapeutic implications in breast cancerEpigenetics and airways diseaseTrials with 'epigenetic' drugs: an updateEpigenetic regulation in estrogen receptor positive breast cancer--role in treatment responseQuantitative assessment of DNA methylation: Potential applications for disease diagnosis, classification, and prognosis in clinical settings.FOXM1 is a transcriptional target of ERalpha and has a critical role in breast cancer endocrine sensitivity and resistanceRepression of androgen receptor transcription through the E2F1/DNMT1 axis.The proteasome inhibitor bortezomib induces an inhibitory chromatin environment at a distal enhancer of the estrogen receptor-α gene.Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cellsEpigenomics and ovarian carcinoma.Hypoxia Represses ER-α Expression and Inhibits Estrogen-Induced Regulation of Ca2+-Activated K+ Channel Activity and Myogenic Tone in Ovine Uterine Arteries: Causal Role of DNA MethylationCancer epigenetics: above and beyondRole of epigenetic modifications in luminal breast cancer.Inhibition of histone deacetylases promotes ubiquitin-dependent proteasomal degradation of DNA methyltransferase 1 in human breast cancer cells.Implication of abnormal epigenetic patterns for human diseases.Epigenetic targeting in breast cancer: therapeutic impact and future direction.Augmentation of effects of interferon-stimulated genes by reversal of epigenetic silencing: potential application to melanoma.Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype.Epigenomics and breast cancerRelB NF-kappaB represses estrogen receptor alpha expression via induction of the zinc finger protein Blimp1.Aberrant promoter CpG methylation and its translational applications in breast cancer.ER re-expression and re-sensitization to endocrine therapies in ER-negative breast cancers.Epigenetic mechanisms of regulation of Foxp3 expression.The silent estrogen receptor--can we make it speak?Inhibition of de novo Methyltransferase 3B is a Potential Therapy for Hepatocellular Carcinoma.miRNAs involved in LY6K and estrogen receptor α contribute to tamoxifen-susceptibility in breast cancer.Oestrogen receptor negativity in breast cancer: a cause or consequence?Cytosine methyltransferases as tumor markers.Endocrine resistance in breast cancer: molecular pathways and rational development of targeted therapies.Epigenetics of estrogen receptor-negative primary breast cancer.Chromatin landscape and endocrine response in breast cancer.Aberrant DNA methylation in human cancers.Epigenetic therapy for solid tumors: from bench science to clinical trials.Mutant p53 binds to estrogen receptor negative promoter via DNMT1 and HDAC1 in MDA-MB-468 breast cancer cells.Scriptaid effects on breast cancer cell lines.The RNA-binding protein HuR regulates GATA3 mRNA stability in human breast cancer cell lines.DNA methyltransferase-mediated transcriptional silencing in malignant glioma: a combined whole-genome microarray and promoter array analysis.Transcription factor decoy against promoter C of estrogen receptor alpha gene induces a functional ER alpha protein in breast cancer cells.miRNA-148a regulates the expression of the estrogen receptor through DNMT1-mediated DNA methylation in breast cancer cells.
P2860
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P2860
Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Specific inhibition of DNMT1 b ...... uman breast cancer cell lines.
@en
Specific inhibition of DNMT1 b ...... ion of estrogen receptor-alpha
@nl
type
label
Specific inhibition of DNMT1 b ...... uman breast cancer cell lines.
@en
Specific inhibition of DNMT1 b ...... ion of estrogen receptor-alpha
@nl
prefLabel
Specific inhibition of DNMT1 b ...... uman breast cancer cell lines.
@en
Specific inhibition of DNMT1 b ...... ion of estrogen receptor-alpha
@nl
P2093
P356
P1476
Specific inhibition of DNMT1 b ...... human breast cancer cell lines
@en
P2093
Dawn Smith
James G Herman
Nancy E Davidson
William G Nelson
P304
P356
10.4161/CBT.2.5.469
P577
2003-09-01T00:00:00Z