Differential modulation of human basophil functions through prostaglandin D2 receptors DP and chemoattractant receptor-homologous molecule expressed on Th2 cells/DP2.
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The deleterious role of basophils in systemic lupus erythematosusExpression of DP2 (CRTh2), a prostaglandin D₂ receptor, in human mast cells.Essential role for hematopoietic prostaglandin D2 synthase in the control of delayed type hypersensitivity.Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation.Prostaglandin D2 Attenuates Bleomycin-Induced Lung Inflammation and Pulmonary FibrosisSphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell functionMast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulation.CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation.Prostaglandin D₂ and T(H)2 inflammation in the pathogenesis of bronchial asthma.Induction of apoptosis in non-small cell lung carcinoma A549 cells by PGD₂ metabolite, 15d-PGJ₂.Association of CRTH2 gene polymorphisms with the required dose of antihistamines in patients with chronic urticaria.The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation.Prostanoid receptor expression in colorectal cancer related to tumor stage, differentiation and progression.Mast cell-derived prostaglandin D2 controls hyaluronan synthesis in human orbital fibroblasts via DP1 activation: implications for thyroid eye disease.Prostaglandins and Their Receptors in Eosinophil Function and As Therapeutic Targets.The CRTH2 agonist Pyl A prevents lipopolysaccharide-induced fetal death but induces preterm labour.Preclinical Safety Profile of a Depleting Antibody against CRTh2 for Asthma: Well Tolerated Despite Unexpected CRTh2 Expression on Vascular Pericytes in the Central Nervous System and Gastric Mucosa.Neuroendocrine cells derived chemokine vasoactive intestinal polypeptide (VIP) in allergic diseases.Prostaglandin D2 amplifies lupus disease through basophil accumulation in lymphoid organs.
P2860
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P2860
Differential modulation of human basophil functions through prostaglandin D2 receptors DP and chemoattractant receptor-homologous molecule expressed on Th2 cells/DP2.
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2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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name
Differential modulation of hum ...... le expressed on Th2 cells/DP2.
@en
Differential modulation of hum ...... le expressed on Th2 cells/DP2.
@nl
type
label
Differential modulation of hum ...... le expressed on Th2 cells/DP2.
@en
Differential modulation of hum ...... le expressed on Th2 cells/DP2.
@nl
prefLabel
Differential modulation of hum ...... le expressed on Th2 cells/DP2.
@en
Differential modulation of hum ...... le expressed on Th2 cells/DP2.
@nl
P2093
P2860
P1476
Differential modulation of hum ...... le expressed on Th2 cells/DP2.
@en
P2093
Matsushima K
Shichijo M
Yamaguchi M
Yamamoto K
Yoshimura-Uchiyama C
P2860
P304
P356
10.1111/J.1365-2222.2004.02027.X
P577
2004-08-01T00:00:00Z