A new model of dual interacting ligand binding sites on integrin alphaIIbbeta3.
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RETRACTED: TGFβ1 signaling via αVβ6 integrinSelection and structure of ion-selective ligands for platelet integrin alpha IIb(beta) 3Structural basis for distinctive recognition of fibrinogen γC peptide by the platelet integrin α IIb β 3Internal Binding of Halogenated Phenols in Dehaloperoxidase-Hemoglobin Inhibits Peroxidase FunctionOrbofiban: an orally active GPIIb/IIIa platelet receptor antagonistDistinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformationRGD-containing peptides inhibit fibrinogen binding to platelet alpha(IIb)beta3 by inducing an allosteric change in the amino-terminal portion of alpha(IIb)Functional binding of hexanucleotides to 3C protease of hepatitis A virus.The chemokine fractalkine can activate integrins without CX3CR1 through direct binding to a ligand-binding site distinct from the classical RGD-binding site.Multi-step fibrinogen binding to the integrin (alpha)IIb(beta)3 detected using force spectroscopy.Proinflammatory secreted phospholipase A2 type IIA (sPLA-IIA) induces integrin activation through direct binding to a newly identified binding site (site 2) in integrins αvβ3, α4β1, and α5β1.Elevating local concentrations of GPIIb-IIIa antagonists counteracts platelet thrombus stability.Identification and characterization of two cation binding sites in the integrin beta 3 subunit.Small molecule inhibitors induce conformational changes in the I domain and the I-like domain of lymphocyte function-associated antigen-1. Molecular insights into integrin inhibition.Probing chemical and conformational differences in the resting and active conformers of platelet integrin alpha(IIb)beta(3).Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin alpha(IIb)beta(3).Bivalent sequential binding model of a Bacillus thuringiensis toxin to gypsy moth aminopeptidase N receptor.The platelet integrin alphaIIbbeta3 binds to the RGD and AGD motifs in fibrinogen.Evidence that ligand and metal ion binding to integrin alpha 4beta 1 are regulated through a coupled equilibrium.Flow cytometric detection of activated mouse integrin alphaIIbbeta3 with a novel monoclonal antibody.Agonist-specific structural rearrangements of integrin alpha IIbbeta 3. Confirmation of the bent conformation in platelets at rest and after activation.Inhibition and reversal of platelet aggregation by alphaIIbbeta3 antagonists depends on the anticoagulant and flow conditions: differential effects of Abciximab and Lamifiban.Secreted Phospholipase A2 Type IIA (sPLA2-IIA) Activates Integrins in an Allosteric Manner.
P2860
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P2860
A new model of dual interacting ligand binding sites on integrin alphaIIbbeta3.
description
1999 nî lūn-bûn
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1999年の論文
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1999年学术文章
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1999年学术文章
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1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
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1999年學術文章
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1999年學術文章
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name
A new model of dual interacting ligand binding sites on integrin alphaIIbbeta3.
@en
A new model of dual interacting ligand binding sites on integrin alphaIIbbeta3.
@nl
type
label
A new model of dual interacting ligand binding sites on integrin alphaIIbbeta3.
@en
A new model of dual interacting ligand binding sites on integrin alphaIIbbeta3.
@nl
prefLabel
A new model of dual interacting ligand binding sites on integrin alphaIIbbeta3.
@en
A new model of dual interacting ligand binding sites on integrin alphaIIbbeta3.
@nl
P2093
P2860
P356
P1476
A new model of dual interacting ligand binding sites on integrin alphaIIbbeta3.
@en
P2093
P2860
P304
P356
10.1074/JBC.274.8.4633
P407
P577
1999-02-01T00:00:00Z