Theodor Bücher Lecture. Metabolomics, modelling and machine learning in systems biology - towards an understanding of the languages of cells. Delivered on 3 July 2005 at the 30th FEBS Congress and the 9th IUBMB conference in Budapest.
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A consensus yeast metabolic network reconstruction obtained from a community approach to systems biologyHow drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusionMolecular phenotyping of a UK population: defining the human serum metabolomeTowards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesIndividuality, phenotypic differentiation, dormancy and 'persistence' in culturable bacterial systems: commonalities shared by environmental, laboratory, and clinical microbiologyFitting Transporter Activities to Cellular Drug Concentrations and Fluxes: Why the Bumblebee Can FlyEvent-based text mining for biology and functional genomicsLarge-scale sequestration of atmospheric carbon via plant roots in natural and agricultural ecosystems: why and howReverse engineering and identification in systems biology: strategies, perspectives and challengesMetabolomics and systems pharmacology: why and how to model the human metabolic network for drug discoveryGrowth control of the eukaryote cell: a systems biology study in yeastA Dormant Microbial Component in the Development of PreeclampsiaIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesExploiting genomic knowledge in optimising molecular breeding programmes: algorithms from evolutionary computingRapid Prediction of Bacterial Heterotrophic Fluxomics Using Machine Learning and Constraint ProgrammingA Bacterial Component to Alzheimer’s-Type Dementia Seen via a Systems Biology Approach that Links Iron Dysregulation and Inflammagen Shedding to DiseaseAutomated tracking of gene expression in individual cells and cell compartments.Joint MS-based platforms for comprehensive comparison of rat plasma and serum metabolic profiling.Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems.Systems chemical biologyOptimization in computational systems biology.Predicting the outcomes of organic reactions via machine learning: are current descriptors sufficient?Automated refinement and inference of analytical models for metabolic networksEnzyme kinetics informatics: from instrument to browser.Computational reasoning across multiple modelsThe dormant blood microbiome in chronic, inflammatory diseases.Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it.An analysis of a 'community-driven' reconstruction of the human metabolic networkReflections on the theory of "silver bullet" octreotide tracers: implications for ligand-receptor interactions in the age of peptides, heterodimers, receptor mosaics, truncated receptors, and multifractal analysis.On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death.Computational modeling of mitochondrial function.Metabolomic approaches to phenotype characterization and applications to complex diseases.Computational systems chemical biology.Gender-dependent progression of systemic metabolic states in early childhood.A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes.Affinity-capture tandem mass spectrometric characterization of polyprenyl-linked oligosaccharides: tool to study protein N-glycosylation pathways.Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy.The role of metabolites and metabolomics in clinically applicable biomarkers of disease.Spectroscopic and statistical methods in metabonomics.Protein damage in diabetes and uremia--identifying hotspots of proteome damage where minimal modification is amplified to marked pathophysiological effect.
P2860
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P2860
Theodor Bücher Lecture. Metabolomics, modelling and machine learning in systems biology - towards an understanding of the languages of cells. Delivered on 3 July 2005 at the 30th FEBS Congress and the 9th IUBMB conference in Budapest.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Theodor Bücher Lecture. Metabo ...... IUBMB conference in Budapest.
@en
Theodor Bücher Lecture. Metabo ...... IUBMB conference in Budapest.
@nl
type
label
Theodor Bücher Lecture. Metabo ...... IUBMB conference in Budapest.
@en
Theodor Bücher Lecture. Metabo ...... IUBMB conference in Budapest.
@nl
prefLabel
Theodor Bücher Lecture. Metabo ...... IUBMB conference in Budapest.
@en
Theodor Bücher Lecture. Metabo ...... IUBMB conference in Budapest.
@nl
P2860
P1433
P1476
Theodor Bücher Lecture. Metabo ...... IUBMB conference in Budapest.
@en
P2860
P304
P356
10.1111/J.1742-4658.2006.05136.X
P407
P50
P577
2006-03-01T00:00:00Z