Bruton's Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats.

about

First-in-human phase 1 study of the BTK inhibitor GDC-0853 in relapsed or refractory B-cell NHL and CLL.

P2860

Q52645845-EE052B59-28AC-472A-953B-17B21BC2AEBC

P2860

Bruton's Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats.

Item

http://www.wikidata.org/entity/Q46217363

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年学术文章

@wuu

2016年学术文章

@zh

2016年学术文章

@zh-cn

2016年学术文章

@zh-hans

2016年学术文章

@zh-my

2016年学术文章

@zh-sg

2016年學術文章

@yue

2016年學術文章

@zh-hant

name

Bruton's Tyrosine Kinase Small ...... t Pancreatic Toxicity in Rats.

@en

Bruton's Tyrosine Kinase Small ...... t Pancreatic Toxicity in Rats.

@nl

type

Item

label

Bruton's Tyrosine Kinase Small ...... t Pancreatic Toxicity in Rats.

@en

Bruton's Tyrosine Kinase Small ...... t Pancreatic Toxicity in Rats.

@nl

prefLabel

Bruton's Tyrosine Kinase Small ...... t Pancreatic Toxicity in Rats.

@en

Bruton's Tyrosine Kinase Small ...... t Pancreatic Toxicity in Rats.

@nl

P1476

Bruton's Tyrosine Kinase Small ...... ct Pancreatic Toxicity in Rats

@en

P2093

Adam R Johnson

http://www.w3.org/2001/XMLSchema#string

Arna Katewa

http://www.w3.org/2001/XMLSchema#string

Dinah L Misner

http://www.w3.org/2001/XMLSchema#string

Donna M Dambach

http://www.w3.org/2001/XMLSchema#string

Fiona Zhong

http://www.w3.org/2001/XMLSchema#string

Harvey Wong

http://www.w3.org/2001/XMLSchema#string

Jacqueline M Tarrant

http://www.w3.org/2001/XMLSchema#string

Jed Ross

http://www.w3.org/2001/XMLSchema#string

Karin Reif

http://www.w3.org/2001/XMLSchema#string

Karin Staflin

http://www.w3.org/2001/XMLSchema#string

P2860

Ibrutinib in mantle cell lymphoma patients: glass half full? Evidence and opinion

Diabetic complications in obese type 2 diabetic rat models

Study for collecting background data on Wistar Hannover [Crl:WI(Han)] rats in general toxicity studies--comparative data to Sprague Dawley rats.

Islet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK rat

Ibrutinib inhibits BCR and NF-κB signaling and reduces tumor proliferation in tissue-resident cells of patients with CLL

Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase.

X-linked agammaglobulinemia.

Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling.

Absence of Tec family kinases interleukin-2 inducible T cell kinase (Itk) and Bruton's tyrosine kinase (Btk) severely impairs Fc epsilonRI-dependent mast cell responses.

Tyrosine kinase Btk is required for NK cell activation

P304

226-238

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1124/JPET.116.236224

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

360

http://www.w3.org/2001/XMLSchema#string

P50

James J Crawford

P577

2016-11-07T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

27821712

http://www.w3.org/2001/XMLSchema#string

Bruton's Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats.

about

P2860

P2860

Bruton's Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698