NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production.
about
The airbag problem-a potential culprit for bench-to-bedside translational efforts: relevance for Alzheimer's diseaseAmyloid beta: multiple mechanisms of toxicity and only some protective effects?APP intracellular domain-WAVE1 pathway reduces amyloid-β production.Trafficking and proteolytic processing of APPMolecular mechanisms of cognitive dysfunction following traumatic brain injuryThe KATP channel activator diazoxide ameliorates amyloid-β and tau pathologies and improves memory in the 3xTgAD mouse model of Alzheimer's disease.Spatial relationship between synapse loss and beta-amyloid deposition in Tg2576 mice.High-resolution bioelectrical imaging of Aβ-induced network dysfunction on CMOS-MEAs for neurotoxicity and rescue studies.Antidepressants are a rational complementary therapy for the treatment of Alzheimer's disease.Interactions between chemokines: regulation of fractalkine/CX3CL1 homeostasis by SDF/CXCL12 in cortical neurons.Endogenous amyloidogenesis in long-term rat hippocampal cell cultures.An overview of APP processing enzymes and products.Amyloid-β as a modulator of synaptic plasticityThe amyloid beta ion channel hypothesis of Alzheimer's disease.AMPA receptor activation promotes non-amyloidogenic amyloid precursor protein processing and suppresses neuronal amyloid-β productionRestored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer's diseaseVitamin C deficiency in the brain impairs cognition, increases amyloid accumulation and deposition, and oxidative stress in APP/PSEN1 and normally aging mice.Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivoN-cadherin enhances APP dimerization at the extracellular domain and modulates Aβ production.Soluble α-synuclein is a novel modulator of Alzheimer's disease pathophysiology.NMDA Neurotransmission Dysfunction in Behavioral and Psychological Symptoms of Alzheimer's Disease.Glutamate system, amyloid ß peptides and tau protein: functional interrelationships and relevance to Alzheimer disease pathologyNeuronal activity and secreted amyloid β lead to altered amyloid β precursor protein and presenilin 1 interactionsPhysiological roles for amyloid beta peptides.Brain aerobic glycolysis functions and Alzheimer's diseaseThe complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease.Beta-site amyloid precursor protein-cleaving enzyme-1 (BACE1)-mediated changes of endogenous amyloid beta in wild-type and transgenic mice in vivo.Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivoPeripheral biomarkers in Autism: secreted amyloid precursor protein-alpha as a probable key player in early diagnosisThe comorbidity of HIV-associated neurocognitive disorders and Alzheimer's disease: a foreseeable medical challenge in post-HAART eraSoluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport.Memantine lowers amyloid-beta peptide levels in neuronal cultures and in APP/PS1 transgenic mice.Review: disruption of the postsynaptic density in Alzheimer's disease and other neurodegenerative dementias.TRPM2, calcium and neurodegenerative diseases.Synapses, NMDA receptor activity and neuronal Aβ production in Alzheimer's disease.Aβ toxicity in Alzheimer's disease.Consequences of inhibiting amyloid precursor protein processing enzymes on synaptic function and plasticity.Neurodegeneration, β-amyloid and mood disorders: state of the art and future perspectives.Deregulation of excitatory neurotransmission underlying synapse failure in Alzheimer's disease.Developmental neuroplasticity and the origin of neurodegenerative diseases.
P2860
Q26991654-CA0DC423-A04E-4C0C-BED7-793C0177B673Q27008826-9098A998-C8AE-4374-AD35-E25B558D812BQ27315195-6610E3BE-B84B-4D23-BA38-09B19F4AEEAAQ28265871-0A9F1C05-5F5B-4AB8-A510-31FEB169FCA7Q28385324-777B915A-CE26-4B48-881A-19FB226BC84EQ30497430-D983CB79-5036-4FEE-BA69-3111542B0522Q33263907-0506E538-3841-4275-9FEA-86EC8ACCE083Q33732756-B45F633F-4AAA-4A99-BDE2-AA2F860A9498Q33751924-0CA46556-AB32-4A96-A7AD-9D6165C47B94Q33796131-D3E2EDB3-4D53-4CA8-BAD8-97BE2CC23631Q33898367-45E76457-AB54-44D8-A02C-91DA159B4D93Q33927819-608E54DD-739C-42E0-9C16-8038A954E07FQ34814145-AC392CFE-C506-497E-A8B8-ADDC2DBEA367Q34965996-D451CC68-F156-40EE-8FE0-7960610C7891Q35036124-6918B0F9-F432-4EF2-9E2E-28CFEC5F8CA6Q35161465-A5CDE0B2-9015-4ED0-8B22-1ABE76670624Q35764820-8557F5AE-6292-44F8-AC68-070D5F06C61DQ35898161-DF8644C7-85B0-493B-9A91-FAA465B89ABCQ36090263-DDBD078C-5D57-4E1E-A590-10D6A99DB673Q36182604-7E997DD1-2EF1-4E22-9DEE-FF0BF28014B4Q36310524-A0E5ED82-10AD-46B3-9278-2EF5490BF99AQ36485712-0E65B54B-561A-4326-BD9E-D681C5943315Q36501589-08201BD5-9C6E-4F85-B17D-3C70E1C8B39DQ36523591-B3484EBF-21E2-4A4D-AC5B-1D315631BA73Q36551980-39920ED7-42A2-4378-9D41-101F5CA3A57CQ36600160-6484D9D0-59AE-4E3E-BBB1-257688F02A4BQ36649496-401F0458-8679-4E85-B739-4F779E6B91AFQ36666647-A1448C5C-74AF-4200-BF96-D7773756E24DQ37000171-F2663118-F33A-4462-91DC-F97CFD7622CDQ37193610-91EFE5FD-2F48-41FD-A8C4-C1512C2F8774Q37290158-BB5C08E2-49B5-400D-97E4-C839BB34AC3FQ37440780-ED7D31C8-2F79-4C48-BD4E-6C8ED2970240Q37790804-2745C087-2FF9-4C48-A6AF-4FA4489B498DQ37850688-99AF29C1-D05B-4B3D-968B-87AC476EEF52Q37875108-F642DAE7-437C-4BB2-B5CB-83247D680976Q37993451-EA69AF95-FA31-4017-8393-E41BC3CFEAB0Q38026045-A997B25F-F917-45A4-AEDD-594BBF93181EQ38045223-FCAD2B6A-D576-415A-B624-46DB64AA3BE8Q38106483-7420BC44-2CE2-4D47-9C1F-090DDC5771B9Q38109214-D8388222-7D94-4C54-9C9A-75AD76945CDA
P2860
NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
NMDA receptor activation inhib ...... ronal amyloid-beta production.
@en
NMDA receptor activation inhib ...... ronal amyloid-beta production.
@nl
type
label
NMDA receptor activation inhib ...... ronal amyloid-beta production.
@en
NMDA receptor activation inhib ...... ronal amyloid-beta production.
@nl
prefLabel
NMDA receptor activation inhib ...... ronal amyloid-beta production.
@en
NMDA receptor activation inhib ...... ronal amyloid-beta production.
@nl
P2093
P50
P1476
NMDA receptor activation inhib ...... uronal amyloid-beta production
@en
P2093
Cecília Gabriel
Charles G Glabe
Michel Plotkine
Nicole Croci
P304
P356
10.1523/JNEUROSCI.0849-05.2005
P407
P577
2005-10-01T00:00:00Z